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3cea

From Proteopedia

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[[Image:3cea.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of myo-inositol 2-dehydrogenase (NP_786804.1) from Lactobacillus plantarum at 2.40 A resolution==
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|PDB= 3cea |SIZE=350|CAPTION= <scene name='initialview01'>3cea</scene>, resolution 2.400&Aring;
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<StructureSection load='3cea' size='340' side='right'caption='[[3cea]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Nad+Binding+Site+For+Residue+A+400'>AC1</scene>, <scene name='pdbsite=AC2:Nad+Binding+Site+For+Residue+B+400'>AC2</scene>, <scene name='pdbsite=AC3:Nad+Binding+Site+For+Residue+C+400'>AC3</scene>, <scene name='pdbsite=AC4:Nad+Binding+Site+For+Residue+D+400'>AC4</scene>, <scene name='pdbsite=AC5:Edo+Binding+Site+For+Residue+D+401'>AC5</scene>, <scene name='pdbsite=AC6:Edo+Binding+Site+For+Residue+C+401'>AC6</scene> and <scene name='pdbsite=AC7:Edo+Binding+Site+For+Residue+D+402'>AC7</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
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<table><tr><td colspan='2'>[[3cea]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactiplantibacillus_plantarum_WCFS1 Lactiplantibacillus plantarum WCFS1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CEA FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Inositol_2-dehydrogenase Inositol 2-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.18 1.1.1.18]
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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|GENE= NP_786804.1, iolG1, lp_3605 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=220668 Lactobacillus plantarum WCFS1])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cea OCA], [https://pdbe.org/3cea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cea RCSB], [https://www.ebi.ac.uk/pdbsum/3cea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cea ProSAT], [https://www.topsan.org/Proteins/JCSG/3cea TOPSAN]</span></td></tr>
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}}
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</table>
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== Function ==
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'''Crystal structure of myo-inositol 2-dehydrogenase (NP_786804.1) from Lactobacillus plantarum at 2.40 A resolution'''
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[https://www.uniprot.org/uniprot/F9ULF9_LACPL F9ULF9_LACPL]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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3CEA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Lactobacillus_plantarum_wcfs1 Lactobacillus plantarum wcfs1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEA OCA].
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<jmolCheckbox>
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[[Category: Inositol 2-dehydrogenase]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/3cea_consurf.spt"</scriptWhenChecked>
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[[Category: Lactobacillus plantarum wcfs1]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Single protein]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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</jmolCheckbox>
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[[Category: CL]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cea ConSurf].
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[[Category: EDO]]
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<div style="clear:both"></div>
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[[Category: NAD]]
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__TOC__
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[[Category: jcsg]]
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</StructureSection>
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[[Category: joint center for structural genomic]]
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[[Category: Lactiplantibacillus plantarum WCFS1]]
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[[Category: myo-inositol 2-dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: nad-binding rossmann fold]]
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[[Category: np_786804 1]]
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[[Category: oxidoreductase family]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:03:40 2008''
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Current revision

Crystal structure of myo-inositol 2-dehydrogenase (NP_786804.1) from Lactobacillus plantarum at 2.40 A resolution

PDB ID 3cea

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