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3d1c

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(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_3d1c", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
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[[Image:3d1c.jpg|left|200px]]
 
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==Crystal structure of Flavin-containing Putative Monooxygenase (NP_373108.1) from STAPHYLOCOCCUS AUREUS MU50 at 2.40 A resolution==
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The line below this paragraph, containing "STRUCTURE_3d1c", creates the "Structure Box" on the page.
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<StructureSection load='3d1c' size='340' side='right'caption='[[3d1c]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3d1c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D1C FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d1c OCA], [https://pdbe.org/3d1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d1c RCSB], [https://www.ebi.ac.uk/pdbsum/3d1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d1c ProSAT], [https://www.topsan.org/Proteins/JCSG/3d1c TOPSAN]</span></td></tr>
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{{STRUCTURE_3d1c| PDB=3d1c | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0H3JN45_STAAN A0A0H3JN45_STAAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/3d1c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d1c ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Flavin-containing Monooxygenase (FMO) catalyzed the oxygenation of broad spectrum of substrates. FMO can also serve as biocatalysts in the Baeyer-Villiger reaction in organic synthesis. Here we report the high-resolution crystal structure of a Baeyer-Villiger Flavin-containing Monooxygenase (BVFMO) from methicillin- and vancomycin-resistant Staphylococcus aureus strain MU50. The structure of Staphylococcus aureus FMO should facilitate further development of BVFMO as biocatalysts. A possible role of Staphylococcus aureus FMO in methicillin and vancomycin resistance is discussed. (c) Proteins 2014;. (c) 2014 Wiley Periodicals, Inc.
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'''Crystal structure of Flavin-containing Putative Monooxygenase (NP_373108.1) from STAPHYLOCOCCUS AUREUS MU50 at 2.40 A resolution'''
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Crystal structure of a Baeyer-Villiger Flavin-containing monooxygenase from Staphylococcus aureus MRSA strain MU50.,Hwang WC, Xu Q, Wu B, Godzik A Proteins. 2014 Aug 5. doi: 10.1002/prot.24661. PMID:25092800<ref>PMID:25092800</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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3D1C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D1C OCA].
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<div class="pdbe-citations 3d1c" style="background-color:#fffaf0;"></div>
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[[Category: Single protein]]
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== References ==
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[[Category: Staphylococcus aureus]]
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<references/>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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__TOC__
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[[Category: Flavin-containing putative monooxygenase]]
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</StructureSection>
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[[Category: Jcsg]]
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[[Category: Large Structures]]
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[[Category: Joint center for structural genomic]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Np_373108 1]]
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[[Category: Oxidoreductase]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Pyridine nucleotide-disulphide oxidoreductase]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 22 22:14:58 2008''
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Current revision

Crystal structure of Flavin-containing Putative Monooxygenase (NP_373108.1) from STAPHYLOCOCCUS AUREUS MU50 at 2.40 A resolution

PDB ID 3d1c

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