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3hwr

From Proteopedia

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{{Seed}}
 
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[[Image:3hwr.jpg|left|200px]]
 
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==Crystal structure of PanE/ApbA family ketopantoate reductase (YP_299159.1) from Ralstonia eutropha JMP134 at 2.15 A resolution==
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The line below this paragraph, containing "STRUCTURE_3hwr", creates the "Structure Box" on the page.
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<StructureSection load='3hwr' size='340' side='right'caption='[[3hwr]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3hwr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cupriavidus_pinatubonensis_JMP134 Cupriavidus pinatubonensis JMP134]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HWR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HWR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCN:BICINE'>BCN</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hwr OCA], [https://pdbe.org/3hwr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hwr RCSB], [https://www.ebi.ac.uk/pdbsum/3hwr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hwr ProSAT], [https://www.topsan.org/Proteins/JCSG/3hwr TOPSAN]</span></td></tr>
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{{STRUCTURE_3hwr| PDB=3hwr | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of PanE/ApbA family ketopantoate reductase (YP_299159.1) from Ralstonia eutropha JMP134 at 2.15 A resolution===
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[https://www.uniprot.org/uniprot/Q46RB9_CUPPJ Q46RB9_CUPPJ] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.[RuleBase:RU362068]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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3HWR is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Ralstonia_eutropha_jmp134 Ralstonia eutropha jmp134]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HWR OCA].
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<jmolCheckbox>
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[[Category: 2-dehydropantoate 2-reductase]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hw/3hwr_consurf.spt"</scriptWhenChecked>
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[[Category: Ralstonia eutropha jmp134]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Jcsg]]
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</jmolCheckbox>
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[[Category: Joint center for structural genomic]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hwr ConSurf].
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[[Category: Nadp]]
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<div style="clear:both"></div>
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[[Category: Oxidoreductase]]
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__TOC__
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[[Category: Pane/apba family ketopantoate reductase]]
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</StructureSection>
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[[Category: Pantothenate biosynthesis]]
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[[Category: Cupriavidus pinatubonensis JMP134]]
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[[Category: Protein structure initiative]]
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[[Category: Large Structures]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Yp_299159 1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 1 09:44:47 2009''
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Current revision

Crystal structure of PanE/ApbA family ketopantoate reductase (YP_299159.1) from Ralstonia eutropha JMP134 at 2.15 A resolution

PDB ID 3hwr

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