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4p0e

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==YhdE E33A (p212121 space group)==
==YhdE E33A (p212121 space group)==
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<StructureSection load='4p0e' size='340' side='right' caption='[[4p0e]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='4p0e' size='340' side='right'caption='[[4p0e]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4p0e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P0E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P0E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4p0e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P0E FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yhdE, b3248, JW3217 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p0e OCA], [https://pdbe.org/4p0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p0e RCSB], [https://www.ebi.ac.uk/pdbsum/4p0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p0e ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p0e OCA], [http://pdbe.org/4p0e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p0e RCSB], [http://www.ebi.ac.uk/pdbsum/4p0e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p0e ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NTPPA_ECOLI NTPPA_ECOLI] Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP (PubMed:24210219, PubMed:25658941, PubMed:28811554). Can also hydrolyze TTP and the modified nucleotides 5-methyl-UTP (m(5)UTP), pseudo-UTP and 5-methyl-CTP (m(5)CTP). Has weak activity with CTP (PubMed:24210219, PubMed:25658941). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids (PubMed:24210219, PubMed:25658941). Important in maintenance of cell shape (PubMed:25658941).<ref>PMID:24210219</ref> <ref>PMID:25658941</ref> <ref>PMID:28811554</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Jia, Z]]
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[[Category: Large Structures]]
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[[Category: Jin, J]]
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[[Category: Jia Z]]
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[[Category: Wang, N]]
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[[Category: Jin J]]
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[[Category: Zheng, J]]
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[[Category: Wang N]]
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[[Category: Unknown function]]
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[[Category: Zheng J]]
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[[Category: Yhde e33a p212121]]
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Revision as of 12:35, 1 February 2023

YhdE E33A (p212121 space group)

PDB ID 4p0e

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