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4pxh

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<StructureSection load='4pxh' size='340' side='right'caption='[[4pxh]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4pxh' size='340' side='right'caption='[[4pxh]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4pxh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp._acta_2897 Streptomyces sp. acta 2897]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PXH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PXH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4pxh]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_sp._Acta_2897 Streptomyces sp. Acta 2897]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PXH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=KH4:S-[2-({N-[(2R)-2-HYDROXY-3,3-DIMETHYL-4-(PHOSPHONOOXY)BUTANOYL]-BETA-ALANYL}AMINO)ETHYL]+1H-IMIDAZOLE-4-CARBOTHIOATE'>KH4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=KH4:S-[2-({N-[(2R)-2-HYDROXY-3,3-DIMETHYL-4-(PHOSPHONOOXY)BUTANOYL]-BETA-ALANYL}AMINO)ETHYL]+1H-IMIDAZOLE-4-CARBOTHIOATE'>KH4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4l0e|4l0e]], [[4l0f|4l0f]], [[4pwv|4pwv]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pxh OCA], [https://pdbe.org/4pxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pxh RCSB], [https://www.ebi.ac.uk/pdbsum/4pxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pxh ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sky32 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1001349 Streptomyces sp. Acta 2897]), sky30 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1001349 Streptomyces sp. Acta 2897])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pxh OCA], [http://pdbe.org/4pxh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pxh RCSB], [http://www.ebi.ac.uk/pdbsum/4pxh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pxh ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/F2YRY7_9ACTN F2YRY7_9ACTN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Cytochrome P450|Cytochrome P450]]
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*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Streptomyces sp. acta 2897]]
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[[Category: Streptomyces sp. Acta 2897]]
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[[Category: Unspecific monooxygenase]]
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[[Category: Cryle MJ]]
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[[Category: Cryle, M J]]
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[[Category: Haslinger K]]
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[[Category: Haslinger, K]]
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[[Category: Beta-aminoacyl carrier protein hydroxylase]]
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[[Category: Cytochrome p450 fold]]
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[[Category: Oxidoreductase-protein binding complex]]
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[[Category: Peptidyl carrier protein domain]]
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[[Category: Skyllamycin nrp]]
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Revision as of 07:36, 8 February 2023

Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis in complex with a peptidyl carrier protein domain

PDB ID 4pxh

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