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4pxj

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==Crystallographic structure of the LZII fragment (anti-parallel orientation) from JIP3==
==Crystallographic structure of the LZII fragment (anti-parallel orientation) from JIP3==
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<StructureSection load='4pxj' size='340' side='right' caption='[[4pxj]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
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<StructureSection load='4pxj' size='340' side='right'caption='[[4pxj]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4pxj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PXJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4pxj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PXJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAPK8IP3, JIP3, KIAA1066 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pxj OCA], [https://pdbe.org/4pxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pxj RCSB], [https://www.ebi.ac.uk/pdbsum/4pxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pxj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pxj OCA], [http://pdbe.org/4pxj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pxj RCSB], [http://www.ebi.ac.uk/pdbsum/4pxj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pxj ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/JIP3_HUMAN JIP3_HUMAN]] The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity).
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[https://www.uniprot.org/uniprot/JIP3_HUMAN JIP3_HUMAN] The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Llinas, P]]
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[[Category: Large Structures]]
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[[Category: Menetrey, J]]
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[[Category: Llinas P]]
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[[Category: Axonal transport]]
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[[Category: Menetrey J]]
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[[Category: Leucine zipper]]
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[[Category: Protein binding]]
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[[Category: Scaffold protein]]
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Revision as of 07:36, 8 February 2023

Crystallographic structure of the LZII fragment (anti-parallel orientation) from JIP3

PDB ID 4pxj

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