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Dynein 3D structures

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Current revision (08:01, 8 February 2023) (edit) (undo)
 
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*Dynein light chain complex
*Dynein light chain complex
-
**[[6gzl]], [[6gzj]] - hDYNC 1 + peptide<br />
+
**[[3zke]], [[3zkf]], [[6gzl]], [[6gzj]], [[7d35]] - hDYNC 1 + peptide<br />
-
**[[2xqq]] - hDYNC 2 + peptide<br />
+
**[[2xqq]], [[4d07]], [[7cnu]] - hDYNC 2 + peptide<br />
**[[3p8m]] - hDYNC 2 + GCN4<br />
**[[3p8m]] - hDYNC 2 + GCN4<br />
-
**[[3zke]], [[3zkf]] - hDYNC 1 + NEK9 peptide<br />
 
-
**[[4d07]] - hDYNC 2 + myosin peptide<br />
 
**[[3tq7]] – hDYNC 1 + EB1C/EB3C<br />
**[[3tq7]] – hDYNC 1 + EB1C/EB3C<br />
**[[1f95]], [[1f96]] - rDYNC + peptide – NMR<BR />
**[[1f95]], [[1f96]] - rDYNC + peptide – NMR<BR />
**[[4qh8]], [[4qh7]] - DmDYNC + anastral spindle 2<br />
**[[4qh8]], [[4qh7]] - DmDYNC + anastral spindle 2<br />
-
**[[3dvp]], [[3brl]], [[3e2b]], [[5e0l]], [[5e0m]] - DmDYNC + peptide<BR />
+
**[[3dvp]], [[3brl]], [[3e2b]], [[5e0l]], [[5e0m]], [[7k3j]], [[7k3k]], [[7k3l]] - DmDYNC + peptide<BR />
**[[4ds1]] - yDYNC + nucleoporin Nup129 peptide <br />
**[[4ds1]] - yDYNC + nucleoporin Nup129 peptide <br />
**[[4ht6]] – yDYNC + PAC11 peptide<br />
**[[4ht6]] – yDYNC + PAC11 peptide<br />
**[[6l4p]] – CrDYNC + DYNC heavy chain 1614-1757<br />
**[[6l4p]] – CrDYNC + DYNC heavy chain 1614-1757<br />
 +
**[[7jts]] – CrDYNC + radial spoke protein + microtubules + calmodulin – Cryo EM<br />
 +
**[[7jtk]] – CrDYNC + radial spoke protein + cytochrome b5 heme-binding domain containing protein – Cryo EM<br />
*Dynein intermediate chain
*Dynein intermediate chain
Line 43: Line 43:
**[[3fm7]], [[3glw]], [[2pg1]], [[2p2t]] - DmDYNC intermediate chain + light chain<br />
**[[3fm7]], [[3glw]], [[2pg1]], [[2p2t]] - DmDYNC intermediate chain + light chain<br />
**[[5hyc]] – rbfDYNC 2<br />
**[[5hyc]] – rbfDYNC 2<br />
 +
**[[6pqt]] – CtDYNC N-terminal – ''Chaetomium thermophilum'' - NMR<br />
*Dynein light+intermediate chains
*Dynein light+intermediate chains
Line 50: Line 51:
**[[6b9h]] - hDYNC + protein hook homolog<br />
**[[6b9h]] - hDYNC + protein hook homolog<br />
**[[6rlb]], [[6sc2]] – hDYNC + alkylguanine-DNA alkyltransferase + WD repeat-containing proteins 60+34 – Cryo EM<br />
**[[6rlb]], [[6sc2]] – hDYNC + alkylguanine-DNA alkyltransferase + WD repeat-containing proteins 60+34 – Cryo EM<br />
-
**[[4w7g]] – DYNC – ''Chaetomium thermophilum''<br />
+
**[[4w7g]] – CtDYNC <br />
*Dynein heavy chain
*Dynein heavy chain
Line 56: Line 57:
**[[5nug]], [[6f1v]] – hDYNC – Cryo EM<br />
**[[5nug]], [[6f1v]] – hDYNC – Cryo EM<br />
**[[5owo]] – hDYNC <br />
**[[5owo]] – hDYNC <br />
 +
**[[8dyu]], [[8dyv]] – hDYNC + PAFAH – Cryo EM<br />
**[[5ayh]] – mDYNC <br />
**[[5ayh]] – mDYNC <br />
**[[3err]] - mDYNC microtubule-binding domain/Ser-tRNA synthetase<br />
**[[3err]] - mDYNC microtubule-binding domain/Ser-tRNA synthetase<br />
Line 61: Line 63:
**[[3j1t]] - mDYNC + tubulin α-1B chain<br />
**[[3j1t]] - mDYNC + tubulin α-1B chain<br />
**[[3j1u]] - mDYNC + tubulin α-1B+β-2B chains<br />
**[[3j1u]] - mDYNC + tubulin α-1B+β-2B chains<br />
-
**[[6rza]] - mDYNC + tubulin α-1B+β-2B chains – Cryo EM<r />
+
**[[6rza]], [[6rzb]] - mDYNC microtubule-binding domain + tubulin α-1B+β-2B chains – Cryo EM<r />
**[[6kjn]] – yDYNC 3095-3232 - NMR<br />
**[[6kjn]] – yDYNC 3095-3232 - NMR<br />
**[[6kjo]] – yDYNC 3095-3232 (mutant) - NMR<br />
**[[6kjo]] – yDYNC 3095-3232 (mutant) - NMR<br />
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**[[2rr7]] – CrDYNC microtubule-binding domain<br />
**[[2rr7]] – CrDYNC microtubule-binding domain<br />
**[[3j6p]] - DYNC + tubulin α-1B chain – slime mold<br />
**[[3j6p]] - DYNC + tubulin α-1B chain – slime mold<br />
 +
**[[6zyy]] – TtDYNC + shulin + ADP + ATP - ''Tetrahymena thermophila'' - Cryo EM<br />
*Dynein motor domain
*Dynein motor domain
**[[4rh7]] – hDYNC + ADP + ATP<br />
**[[4rh7]] – hDYNC + ADP + ATP<br />
 +
**[[7z8f]], [[7z8g]], [[7z8h]], [[7z8i]], [[7z8j]], [[7z8k]], [[7z8l]] – hDYNC (mutant) + ADP + ATP + ANP – Cryo EM<br
 +
**[[6rla]] – hDYNC/alkylguanine-DNA alkyltransferase + ADP + ATP – Cryo EM<br />
**[[3j68]], [[3j67]] – DYNC – sea urchin<br />
**[[3j68]], [[3j67]] – DYNC – sea urchin<br />
**[[4aki]], [[4akg]] – yDYNC + ATP<br />
**[[4aki]], [[4akg]] – yDYNC + ATP<br />
**[[4akh]] – yDYNC + AMPPNP<br />
**[[4akh]] – yDYNC + AMPPNP<br />
**[[4ai6]] – yDYNC + ADP<br />
**[[4ai6]] – yDYNC + ADP<br />
 +
**[[7mi1]] – yDYNC/endolysin <br />
 +
**[[7mi3]], [[7mi6]], [[7mi8]] – yDYNC/endolysin + ATP + pyrimidine derivative – Cryo EM<br />
*Dynein tail
*Dynein tail
-
**[[6f1y]] – hDCTN heavy+light+intermediate – CryoEM<br />
+
**[[6f1y]] – hDYNC heavy+light+intermediate – CryoEM<br />
-
**[[5nvs]] – hDCTN heavy+light+intermediate + LC8 + TcTex + ROBL – CryoEM<br />
+
**[[5nvs]] – hDYNC heavy+light+intermediate + LC8 + TcTex + ROBL – CryoEM<br />
-
**[[5nvu]] – hDCTN motor+heavy+light+intermediate + LC8 + TcTex + ROBL – CryoEM<br />
+
**[[5nvu]] – hDYNC motor+heavy+light+intermediate + LC8 + TcTex + ROBL – CryoEM<br />
-
**[[5nw4]] – hDCTN heavy+light+intermediate + APR1 + APR11 + ROBL + beta-actin + capping protein + dynactin + P150 + BICD2N – CryoEM<br />
+
**[[5nw4]] – hDYNC heavy+light+intermediate + APR1 + APR11 + ROBL + beta-actin + capping protein + dynactin + P150 + BICD2N – CryoEM<br />
-
**[[5afu]] – pDCTN subunits 2,3,5,6 + dynein tail + capping protein - pig – CryoEM<br />
+
**[[5afu]] – pDYNC subunits 2,3,5,6 + dynein tail + capping protein - pig – CryoEM<br />
**[[6f3a]] – pDYNC heavy+light+intermediate + dynactin + BICD2N - Cryo EM<br />
**[[6f3a]] – pDYNC heavy+light+intermediate + dynactin + BICD2N - Cryo EM<br />
**[[6f1u]], [[6f1t]] – pDYNC heavy+light+intermediate + dynactin + BICDR1 - Cryo EM<br />
**[[6f1u]], [[6f1t]] – pDYNC heavy+light+intermediate + dynactin + BICDR1 - Cryo EM<br />
**[[6f38]] – pDYNC heavy+light+intermediate + dynactin + HOOK3 - Cryo EM<br />
**[[6f38]] – pDYNC heavy+light+intermediate + dynactin + HOOK3 - Cryo EM<br />
 +
**[[6zyx]] – TtDYNC heavy+light+intermediate + shulin + GTP - Cryo EM<br />
 +
 +
* Dynein arm core subcomplex
 +
 +
**[[7k58]], [[7k5b]], [[7kek]], [[7kzn]], [[7kzo]] – CrDYNC + DC1 + DC2 – CryoEM<br />
 +
**[[7kzm]] – CrDYNC + DC1 + DC2 + DC3 + GDP + GTP – CryoEM<br />
 +
**[[6zyw]], [[7moq]] – TtDYNC + thioredoxin + shulin + ADP + ATP + GTP – CryoEM <br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of Dynein

Updated on 08-February-2023

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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