|
|
| (One intermediate revision not shown.) |
| Line 1: |
Line 1: |
| - | ==Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Tyr-Ala-Y(PO2CH2)-homoPhe-OH==
| + | #REDIRECT [[6i6z]] This PDB entry is obsolete and replaced by 6i6z |
| - | <StructureSection load='4uef' size='340' side='right' caption='[[4uef]], [[Resolution|resolution]] 1.69Å' scene=''>
| + | |
| - | == Structural highlights ==
| + | |
| - | <table><tr><td colspan='2'>[[4uef]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UEF FirstGlance]. <br>
| + | |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TJE:(2S)-2-{[(S)-{(1R)-1-[(N-ACETYL-L-TYROSYL)AMINO]ETHYL}(HYDROXY)PHOSPHORYL]METHYL}-4-PHENYLBUTANOIC+ACID'>TJE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
| + | |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uee|4uee]]</td></tr>
| + | |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>
| + | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uef OCA], [http://pdbe.org/4uef PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uef RCSB], [http://www.ebi.ac.uk/pdbsum/4uef PDBsum]</span></td></tr>
| + | |
| - | </table>
| + | |
| - | == Function ==
| + | |
| - | [[http://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN]] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref>
| + | |
| - | == References ==
| + | |
| - | <references/>
| + | |
| - | __TOC__
| + | |
| - | </StructureSection>
| + | |
| - | [[Category: Carboxypeptidase A]]
| + | |
| - | [[Category: Aviles, F X]]
| + | |
| - | [[Category: Costenaro, L]]
| + | |
| - | [[Category: Covaleda, G]]
| + | |
| - | [[Category: Devel, L]]
| + | |
| - | [[Category: Dive, V]]
| + | |
| - | [[Category: Gallego, P]]
| + | |
| - | [[Category: Reverter, D]]
| + | |
| - | [[Category: Cpa1]]
| + | |
| - | [[Category: Hydrolase]]
| + | |
| - | [[Category: Phosphinic inhibitor]]
| + | |
