This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7wvb
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state== | |
| - | + | <StructureSection load='7wvb' size='340' side='right'caption='[[7wvb]], [[Resolution|resolution]] 2.09Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7wvb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WVB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wvb OCA], [https://pdbe.org/7wvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wvb RCSB], [https://www.ebi.ac.uk/pdbsum/7wvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wvb ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Cao | + | == Disease == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/F16P1_HUMAN F16P1_HUMAN] Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:[https://omim.org/entry/229700 229700]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.<ref>PMID:9382095</ref> <ref>PMID:12126934</ref> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/F16P1_HUMAN F16P1_HUMAN] |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cao Y]] | ||
| + | [[Category: Chen Y]] | ||
| + | [[Category: Li C]] | ||
| + | [[Category: Zhang J]] | ||
Revision as of 10:23, 15 February 2023
Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state
| |||||||||||
Categories: Homo sapiens | Large Structures | Cao Y | Chen Y | Li C | Zhang J
