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2lhl

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==Chemical Shift Assignments and solution structure of human apo-S100A1 E32Q mutant==
==Chemical Shift Assignments and solution structure of human apo-S100A1 E32Q mutant==
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<StructureSection load='2lhl' size='340' side='right'caption='[[2lhl]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2lhl' size='340' side='right'caption='[[2lhl]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lhl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LHL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2lhl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LHL FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2l0p|2l0p]]</div></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhl OCA], [https://pdbe.org/2lhl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lhl RCSB], [https://www.ebi.ac.uk/pdbsum/2lhl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lhl ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">S100A1, S100A ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhl OCA], [https://pdbe.org/2lhl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lhl RCSB], [https://www.ebi.ac.uk/pdbsum/2lhl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lhl ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/S10A1_HUMAN S10A1_HUMAN]] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
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[https://www.uniprot.org/uniprot/S10A1_HUMAN S10A1_HUMAN] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bierzynski, A]]
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[[Category: Bierzynski A]]
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[[Category: Ejchart, A]]
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[[Category: Ejchart A]]
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[[Category: Ruszczynska-Bartnik, K]]
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[[Category: Ruszczynska-Bartnik K]]
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[[Category: Zdanowski, K]]
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[[Category: Zdanowski K]]
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[[Category: Zhukov, I]]
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[[Category: Zhukov I]]
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[[Category: 15n relaxation]]
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[[Category: Calcium binding protein]]
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[[Category: Metal binding protein]]
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[[Category: S100 protein family]]
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Revision as of 11:00, 15 February 2023

Chemical Shift Assignments and solution structure of human apo-S100A1 E32Q mutant

PDB ID 2lhl

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