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2ljv

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Current revision (11:04, 15 February 2023) (edit) (undo)
 
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==Solution structure of Rhodostomin G50L mutant==
==Solution structure of Rhodostomin G50L mutant==
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<StructureSection load='2ljv' size='340' side='right'caption='[[2ljv]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2ljv' size='340' side='right'caption='[[2ljv]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ljv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agkistrodon_rhodostoma Agkistrodon rhodostoma]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LJV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ljv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LJV FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RHOD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Agkistrodon rhodostoma])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ljv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ljv OCA], [https://pdbe.org/2ljv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ljv RCSB], [https://www.ebi.ac.uk/pdbsum/2ljv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ljv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ljv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ljv OCA], [https://pdbe.org/2ljv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ljv RCSB], [https://www.ebi.ac.uk/pdbsum/2ljv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ljv ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
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[https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Agkistrodon rhodostoma]]
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[[Category: Calloselasma rhodostoma]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chang, Y]]
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[[Category: Chang Y]]
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[[Category: Chen, C]]
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[[Category: Chen C]]
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[[Category: Chen, Y]]
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[[Category: Chen Y]]
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[[Category: Chuang, W]]
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[[Category: Chuang W]]
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[[Category: Huang, C]]
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[[Category: Huang C]]
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[[Category: Shiu, J]]
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[[Category: Shiu J]]
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[[Category: Disintegrin]]
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[[Category: Hydrolase]]
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[[Category: Integrin]]
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[[Category: Rgd]]
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Current revision

Solution structure of Rhodostomin G50L mutant

PDB ID 2ljv

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