This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4qi9
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='4qi9' size='340' side='right'caption='[[4qi9]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='4qi9' size='340' side='right'caption='[[4qi9]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4qi9]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4qi9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_CO92 Yersinia pestis CO92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QI9 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qi9 OCA], [https://pdbe.org/4qi9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qi9 RCSB], [https://www.ebi.ac.uk/pdbsum/4qi9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qi9 ProSAT]</span></td></tr> | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/A0A3N4BLI0_YERPE A0A3N4BLI0_YERPE] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[ARBA:ARBA00025067][PIRNR:PIRNR000194] |
==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Dihydrofolate reductase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Yersinia pestis | + | [[Category: Yersinia pestis CO92]] |
| - | [[Category: Anderson | + | [[Category: Anderson WF]] |
| - | + | [[Category: Joachimiak A]] | |
| - | [[Category: Joachimiak | + | [[Category: Kim Y]] |
| - | [[Category: Kim | + | [[Category: Makowska-Grzyska M]] |
| - | [[Category: Makowska-Grzyska | + | [[Category: Maltseva N]] |
| - | [[Category: Maltseva | + | [[Category: Mulligan R]] |
| - | [[Category: Mulligan | + | [[Category: Shatsman S]] |
| - | [[Category: Shatsman | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 11:31, 15 February 2023
Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate
| |||||||||||
