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4qmg

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==The Structure of MTDH-SND1 Complex Reveals Novel Cancer-Promoting Interactions==
==The Structure of MTDH-SND1 Complex Reveals Novel Cancer-Promoting Interactions==
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<StructureSection load='4qmg' size='340' side='right' caption='[[4qmg]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='4qmg' size='340' side='right'caption='[[4qmg]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qmg]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QMG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QMG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qmg]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QMG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QMG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qmg OCA], [https://pdbe.org/4qmg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qmg RCSB], [https://www.ebi.ac.uk/pdbsum/4qmg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qmg ProSAT]</span></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3omc|3omc]], [[2e6n|2e6n]], [[3omg|3omg]], [[3bdl|3bdl]], [[2hqe|2hqe]], [[2hqx|2hqx]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qmg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qmg RCSB], [http://www.ebi.ac.uk/pdbsum/4qmg PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4qmg" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Guo, F.]]
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[[Category: Homo sapiens]]
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[[Category: Kang, Y.]]
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[[Category: Large Structures]]
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[[Category: Satyshur, K.]]
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[[Category: Guo F]]
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[[Category: Stanevich, V.]]
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[[Category: Kang Y]]
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[[Category: Wan, L.]]
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[[Category: Satyshur K]]
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[[Category: Xing, Y.]]
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[[Category: Stanevich V]]
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[[Category: Breast cancer]]
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[[Category: Wan L]]
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[[Category: Dna/rna-binding]]
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[[Category: Xing Y]]
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[[Category: Mirna-mediated silencing]]
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[[Category: Mtdh]]
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[[Category: Nuclease]]
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[[Category: Sn domain]]
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[[Category: Snd1]]
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[[Category: Transcription]]
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[[Category: Tumorigenesis]]
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Current revision

The Structure of MTDH-SND1 Complex Reveals Novel Cancer-Promoting Interactions

PDB ID 4qmg

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