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4qnn
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==Crystal Structure of phospholipase A 1 from hornet(Vespa basalis) venom== | ==Crystal Structure of phospholipase A 1 from hornet(Vespa basalis) venom== | ||
| - | <StructureSection load='4qnn' size='340' side='right' caption='[[4qnn]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='4qnn' size='340' side='right'caption='[[4qnn]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4qnn]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4qnn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vespa_basalis Vespa basalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QNN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QNN FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qnn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qnn OCA], [https://pdbe.org/4qnn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qnn RCSB], [https://www.ebi.ac.uk/pdbsum/4qnn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qnn ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PA1_VESBA PA1_VESBA] Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity). Shows potent hemolytic activity that is responsible for its lethal effect (PubMed:26603193). May act as an allergen (By similarity). In vivo, induces local inflammatory effects (PubMed:7687388).[UniProtKB:P0DMB4]<ref>PMID:7687388</ref> <ref>PMID:26603193</ref> | ||
==See Also== | ==See Also== | ||
*[[Phospholipase A1|Phospholipase A1]] | *[[Phospholipase A1|Phospholipase A1]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Vespa basalis]] |
| - | [[Category: | + | [[Category: Chuang CY]] |
| - | [[Category: | + | [[Category: Hou MH]] |
| - | [[Category: | + | [[Category: Ko TP]] |
| - | [[Category: | + | [[Category: Wang AHJ]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of phospholipase A 1 from hornet(Vespa basalis) venom
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Categories: Large Structures | Vespa basalis | Chuang CY | Hou MH | Ko TP | Wang AHJ
