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Lenalidomide
From Proteopedia
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<scene name='95/954025/Cv/4'>Lenalidomide</scene>, sold under the trade name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). See also [https://en.wikipedia.org/wiki/Lenalidomide]. | <scene name='95/954025/Cv/4'>Lenalidomide</scene>, sold under the trade name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). See also [https://en.wikipedia.org/wiki/Lenalidomide]. | ||
| - | On a molecular level, <scene name='95/954025/Cv/3'>lenalidomide has been shown to interact with the ubiquitin E3 ligase cereblon</scene> and target this enzyme to degrade the Ikaros transcription factors IKZF1 and IKZF3. | + | On a molecular level, <scene name='95/954025/Cv/3'>lenalidomide has been shown to interact with the ubiquitin E3 ligase cereblon</scene> and target this enzyme to degrade the Ikaros transcription factors IKZF1 and IKZF3. <scene name='95/954025/Cv/5'>Lenalidomide binding site</scene>. |
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 11:40, 27 February 2023
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