This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4ra9
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='4ra9' size='340' side='right'caption='[[4ra9]], [[Resolution|resolution]] 2.05Å' scene=''> | <StructureSection load='4ra9' size='340' side='right'caption='[[4ra9]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ra9]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4ra9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RA9 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ra9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ra9 OCA], [https://pdbe.org/4ra9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ra9 RCSB], [https://www.ebi.ac.uk/pdbsum/4ra9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ra9 ProSAT]</span></td></tr> | |
| - | + | ||
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ASPG_PYRFU ASPG_PYRFU] Catalyzes the hydrolysis of L-asparagine into L-aspartate and ammonia. Displays no glutaminase activity, a highly desirable therapeutic property.<ref>PMID:20370616</ref> <ref>PMID:22166247</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 26: | Line 25: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Asparaginase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Pyrococcus furiosus DSM 3638]] |
[[Category: Ashish]] | [[Category: Ashish]] | ||
| - | [[Category: Kundu | + | [[Category: Kundu B]] |
| - | [[Category: Sharma | + | [[Category: Sharma P]] |
| - | [[Category: Singh | + | [[Category: Singh S]] |
| - | [[Category: Tomar | + | [[Category: Tomar R]] |
| - | [[Category: Yadav | + | [[Category: Yadav SPS]] |
| - | + | ||
Revision as of 06:47, 2 March 2023
Crystal Structure of Conjoint Pyrococcus Furiosus L-asparaginase with Citrate
| |||||||||||
