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8hs3
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8hs3 is ON HOLD Authors: Lin, X., Jiang, S., Xu, F. Description: Gi bound orphan GPR20 in ligand-free state Category: Unreleased Structures [[C...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Gi bound orphan GPR20 in ligand-free state== | |
| - | + | <StructureSection load='8hs3' size='340' side='right'caption='[[8hs3]], [[Resolution|resolution]] 3.14Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8hs3]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HS3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hs3 OCA], [https://pdbe.org/8hs3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hs3 RCSB], [https://www.ebi.ac.uk/pdbsum/8hs3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hs3 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Jiang | + | [https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref> |
| - | [[Category: Lin | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Jiang S]] | ||
| + | [[Category: Lin X]] | ||
| + | [[Category: Xu F]] | ||
Current revision
Gi bound orphan GPR20 in ligand-free state
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