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2vb1

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==HEWL AT 0.65 ANGSTROM RESOLUTION==
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<StructureSection load='2vb1' size='340' side='right' caption='[[2vb1]], [[Resolution|resolution]] 0.65&Aring;' scene=''>
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==HEWL at 0.65 angstrom resolution==
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<StructureSection load='2vb1' size='340' side='right'caption='[[2vb1]], [[Resolution|resolution]] 0.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vb1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VB1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vb1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VB1 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aki|1aki]], [[1azf|1azf]], [[1b2k|1b2k]], [[1bgi|1bgi]], [[1bvx|1bvx]], [[1bwj|1bwj]], [[1c10|1c10]], [[1dpw|1dpw]], [[1dqj|1dqj]], [[1f0w|1f0w]], [[1f10|1f10]], [[1fdl|1fdl]], [[1flq|1flq]], [[1flu|1flu]], [[1flw|1flw]], [[1fn5|1fn5]], [[1g7i|1g7i]], [[1g7l|1g7l]], [[1gwd|1gwd]], [[1gxv|1gxv]], [[1h6m|1h6m]], [[1hc0|1hc0]], [[1hel|1hel]], [[1hen|1hen]], [[1heo|1heo]], [[132l|132l]], [[193l|193l]], [[194l|194l]], [[1a2y|1a2y]], [[1at5|1at5]], [[1at6|1at6]], [[1b0d|1b0d]], [[1bhz|1bhz]], [[1bvk|1bvk]], [[1bwh|1bwh]], [[1bwi|1bwi]], [[1c08|1c08]], [[1dpx|1dpx]], [[1e8l|1e8l]], [[1f3j|1f3j]], [[1fly|1fly]], [[1g7h|1g7h]], [[1g7j|1g7j]], [[1g7m|1g7m]], [[1gpq|1gpq]], [[1gxx|1gxx]], [[1h87|1h87]], [[1hem|1hem]], [[1heq|1heq]], [[1her|1her]], [[1hsw|1hsw]], [[1hep|1hep]], [[1hew|1hew]], [[1hf4|1hf4]], [[1ic4|1ic4]], [[1ic5|1ic5]], [[1ic7|1ic7]], [[1iee|1iee]], [[1io5|1io5]], [[1ioq|1ioq]], [[1ios|1ios]], [[1iot|1iot]], [[1ir7|1ir7]], [[1ir9|1ir9]], [[1j1x|1j1x]], [[1ja2|1ja2]], [[1ja6|1ja6]], [[1jis|1jis]], [[1jit|1jit]], [[1jj0|1jj0]], [[1jj1|1jj1]], [[1jj3|1jj3]], [[1kip|1kip]], [[1kir|1kir]], [[1lcn|1lcn]], [[1hsx|1hsx]], [[1ior|1ior]], [[1ir8|1ir8]], [[1j1o|1j1o]], [[1j1p|1j1p]], [[1ja4|1ja4]], [[1ja7|1ja7]], [[1jiy|1jiy]], [[1jpo|1jpo]], [[1jto|1jto]], [[1jtt|1jtt]], [[1kiq|1kiq]], [[1kxw|1kxw]], [[1kxx|1kxx]], [[1kxy|1kxy]], [[1lj3|1lj3]], [[1lj4|1lj4]], [[1ljf|1ljf]], [[1ljh|1ljh]], [[1ljj|1ljj]], [[1ljk|1ljk]], [[1lkr|1lkr]], [[1lks|1lks]], [[1lpi|1lpi]], [[1lsa|1lsa]], [[1lse|1lse]], [[1lje|1lje]], [[1ljg|1ljg]], [[1lji|1lji]], [[1lma|1lma]], [[1lsb|1lsb]], [[1lsc|1lsc]], [[1lsd|1lsd]], [[1lsf|1lsf]], [[1lsm|1lsm]], [[1lsn|1lsn]], [[1lsy|1lsy]], [[1lys|1lys]], [[1lz9|1lz9]], [[1lzc|1lzc]], [[1lze|1lze]], [[1lzg|1lzg]], [[1lzh|1lzh]], [[1mel|1mel]], [[1n4f|1n4f]], [[1nby|1nby]], [[1ndg|1ndg]], [[1qio|1qio]], [[1ri8|1ri8]], [[1rjc|1rjc]], [[1sf6|1sf6]], [[1sfg|1sfg]], [[1lsg|1lsg]], [[1lsz|1lsz]], [[1lyo|1lyo]], [[1lyz|1lyz]], [[1lz8|1lz8]], [[1lza|1lza]], [[1lzb|1lzb]], [[1lzd|1lzd]], [[1lzn|1lzn]], [[1lzt|1lzt]], [[1mlc|1mlc]], [[1nbz|1nbz]], [[1ndm|1ndm]], [[1p2c|1p2c]], [[1ps5|1ps5]], [[1qtk|1qtk]], [[1rcm|1rcm]], [[1rfp|1rfp]], [[1sf4|1sf4]], [[1sf7|1sf7]], [[1sfb|1sfb]], [[1sq2|1sq2]], [[1t3p|1t3p]], [[1t6v|1t6v]], [[1ua6|1ua6]], [[1uc0|1uc0]], [[1uco|1uco]], [[1uib|1uib]], [[1uif|1uif]], [[1vat|1vat]], [[1vdp|1vdp]], [[1vds|1vds]], [[1vdt|1vdt]], [[1ved|1ved]], [[1vfb|1vfb]], [[1w6z|1w6z]], [[1wtm|1wtm]], [[1wtn|1wtn]], [[1xej|1xej]], [[1xgq|1xgq]], [[1yik|1yik]], [[1ykx|1ykx]], [[1yl0|1yl0]], [[1yqv|1yqv]], [[1zmy|1zmy]], [[2aub|2aub]], [[2bly|2bly]], [[2bpu|2bpu]], [[1uia|1uia]], [[1uic|1uic]], [[1uid|1uid]], [[1uie|1uie]], [[1uig|1uig]], [[1uih|1uih]], [[1uuz|1uuz]], [[1v7s|1v7s]], [[1v7t|1v7t]], [[1vau|1vau]], [[1vdq|1vdq]], [[1xei|1xei]], [[1xek|1xek]], [[1xfp|1xfp]], [[1xgp|1xgp]], [[1yil|1yil]], [[1yky|1yky]], [[1ykz|1ykz]], [[1yl1|1yl1]], [[1z55|1z55]], [[2a6u|2a6u]], [[2a7d|2a7d]], [[2a7f|2a7f]], [[2b5z|2b5z]], [[2blx|2blx]], [[2c8o|2c8o]], [[2c8p|2c8p]], [[2cds|2cds]], [[2d4i|2d4i]], [[2d6b|2d6b]], [[2d91|2d91]], [[2lyo|2lyo]], [[3hfm|3hfm]], [[3lyt|3lyt]], [[3lyz|3lyz]], [[4lyo|4lyo]], [[5lyz|5lyz]], [[6lyt|6lyt]], [[6lyz|6lyz]], [[7lyz|7lyz]], [[8lyz|8lyz]], [[2cgi|2cgi]], [[2d4j|2d4j]], [[2d4k|2d4k]], [[2fbb|2fbb]], [[2hfm|2hfm]], [[2iff|2iff]], [[2lym|2lym]], [[2lyz|2lyz]], [[2lzh|2lzh]], [[2lzt|2lzt]], [[3lym|3lym]], [[3lyo|3lyo]], [[3lzt|3lzt]], [[4lym|4lym]], [[4lyt|4lyt]], [[4lyz|4lyz]], [[4lzt|4lzt]], [[5lym|5lym]], [[5lyt|5lyt]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb1 OCA], [https://pdbe.org/2vb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vb1 RCSB], [https://www.ebi.ac.uk/pdbsum/2vb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vb1 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vb1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb1 PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/2vb1_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/2vb1_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vb1 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2vb1" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Alkire, R.]]
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[[Category: Alkire R]]
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[[Category: Dauter, M.]]
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[[Category: Dauter M]]
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[[Category: Dauter, Z.]]
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[[Category: Dauter Z]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Wang, J.]]
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[[Category: Wang J]]
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[[Category: Allergen]]
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[[Category: Antimicrobial]]
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[[Category: Atomic resolution]]
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[[Category: Bacteriolytic enzyme]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Lysozyme]]
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[[Category: Triclinic hewl]]
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Current revision

HEWL at 0.65 angstrom resolution

PDB ID 2vb1

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