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5k5g

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==Structure of human islet amyloid polypeptide in complex with an engineered binding protein==
==Structure of human islet amyloid polypeptide in complex with an engineered binding protein==
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<StructureSection load='5k5g' size='340' side='right'caption='[[5k5g]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='5k5g' size='340' side='right'caption='[[5k5g]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5k5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K5G OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5K5G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5k5g]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K5G FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IAPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k5g OCA], [https://pdbe.org/5k5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k5g RCSB], [https://www.ebi.ac.uk/pdbsum/5k5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k5g ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5k5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k5g OCA], [http://pdbe.org/5k5g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k5g RCSB], [http://www.ebi.ac.uk/pdbsum/5k5g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k5g ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN]] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
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[https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Synthetic construct sequences]]
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[[Category: Synthetic construct]]
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[[Category: Feuerstein, S]]
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[[Category: Feuerstein S]]
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[[Category: Gremer, L]]
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[[Category: Gremer L]]
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[[Category: Hoyer, W]]
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[[Category: Hoyer W]]
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[[Category: Mirecka, E A]]
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[[Category: Mirecka EA]]
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[[Category: Schroeder, G F]]
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[[Category: Schroeder GF]]
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[[Category: Stoldt, M]]
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[[Category: Stoldt M]]
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[[Category: Willbold, D]]
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[[Category: Willbold D]]
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[[Category: Amyloid]]
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[[Category: Beta-hairpin]]
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[[Category: Hormone]]
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[[Category: Signaling protein]]
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[[Category: Type 2 diabetes]]
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Current revision

Structure of human islet amyloid polypeptide in complex with an engineered binding protein

PDB ID 5k5g

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