This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2miq
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Solution NMR Structure of PHD Type 1 Zinc Finger Domain 1 of Lysine-specific Demethylase Lid from Drosophila melanogaster, Northeast Structural Genomics Consortium (NESG) Target FR824J== | ==Solution NMR Structure of PHD Type 1 Zinc Finger Domain 1 of Lysine-specific Demethylase Lid from Drosophila melanogaster, Northeast Structural Genomics Consortium (NESG) Target FR824J== | ||
| - | <StructureSection load='2miq' size='340' side='right' caption='[[2miq | + | <StructureSection load='2miq' size='340' side='right'caption='[[2miq]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2miq]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2miq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MIQ FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2miq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2miq OCA], [https://pdbe.org/2miq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2miq RCSB], [https://www.ebi.ac.uk/pdbsum/2miq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2miq ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/KDM5_DROME KDM5_DROME] Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Specifically demethylates trimethylated H3 'Lys-4'. Required for the correct regulation of homeotic genes during development.<ref>PMID:11014813</ref> <ref>PMID:17311883</ref> <ref>PMID:17351631</ref> <ref>PMID:17351630</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Drosophila melanogaster]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Eletsky | + | [[Category: Eletsky A]] |
| - | [[Category: Everett | + | [[Category: Everett JK]] |
| - | [[Category: Janjua | + | [[Category: Janjua H]] |
| - | [[Category: Maglaqui | + | [[Category: Maglaqui M]] |
| - | [[Category: Montelione | + | [[Category: Montelione GT]] |
| - | + | [[Category: Shastry R]] | |
| - | [[Category: Shastry | + | [[Category: Sukumaran DK]] |
| - | [[Category: Sukumaran | + | [[Category: Szyperski T]] |
| - | [[Category: Szyperski | + | [[Category: Xiao R]] |
| - | [[Category: Xiao | + | [[Category: Xu X]] |
| - | [[Category: Xu | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution NMR Structure of PHD Type 1 Zinc Finger Domain 1 of Lysine-specific Demethylase Lid from Drosophila melanogaster, Northeast Structural Genomics Consortium (NESG) Target FR824J
| |||||||||||
