1k4r

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1k4r.gif|left|200px]]
[[Image:1k4r.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1k4r |SIZE=350|CAPTION= <scene name='initialview01'>1k4r</scene>, resolution 24.&Aring;
+
The line below this paragraph, containing "STRUCTURE_1k4r", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND=
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1k4r| PDB=1k4r | SCENE= }}
-
|RELATEDENTRY=[[1svb|1svb]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k4r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k4r OCA], [http://www.ebi.ac.uk/pdbsum/1k4r PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1k4r RCSB]</span>
+
-
}}
+
'''Structure of Dengue Virus'''
'''Structure of Dengue Virus'''
Line 37: Line 34:
[[Category: Strauss, J H.]]
[[Category: Strauss, J H.]]
[[Category: Zhang, W.]]
[[Category: Zhang, W.]]
-
[[Category: dengue virus]]
+
[[Category: Dengue virus]]
-
[[Category: flaviviridae]]
+
[[Category: Flaviviridae]]
-
[[Category: flavivirus]]
+
[[Category: Flavivirus]]
-
[[Category: glycoprotein e from tick-borne encephalitis virus]]
+
[[Category: Glycoprotein e from tick-borne encephalitis virus]]
-
[[Category: icosahedral virus]]
+
[[Category: Icosahedral virus]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:18:20 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:43:27 2008''
+

Revision as of 19:18, 2 May 2008

Image:1k4r.gif


PDB ID 1k4r

Drag the structure with the mouse to rotate
1k4r, resolution 24.00Å ()
Related: 1svb
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Structure of Dengue Virus


Overview

The first structure of a flavivirus has been determined by using a combination of cryoelectron microscopy and fitting of the known structure of glycoprotein E into the electron density map. The virus core, within a lipid bilayer, has a less-ordered structure than the external, icosahedral scaffold of 90 glycoprotein E dimers. The three E monomers per icosahedral asymmetric unit do not have quasiequivalent symmetric environments. Difference maps indicate the location of the small membrane protein M relative to the overlaying scaffold of E dimers. The structure suggests that flaviviruses, and by analogy also alphaviruses, employ a fusion mechanism in which the distal beta barrels of domain II of the glycoprotein E are inserted into the cellular membrane.

About this Structure

1K4R is a Single protein structure of sequence from Tick-borne encephalitis virus. Full crystallographic information is available from OCA.

Reference

Structure of dengue virus: implications for flavivirus organization, maturation, and fusion., Kuhn RJ, Zhang W, Rossmann MG, Pletnev SV, Corver J, Lenches E, Jones CT, Mukhopadhyay S, Chipman PR, Strauss EG, Baker TS, Strauss JH, Cell. 2002 Mar 8;108(5):717-25. PMID:11893341 Page seeded by OCA on Fri May 2 22:18:20 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1k4r"
Personal tools