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Antibody 3D structures
From Proteopedia
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*Fab | *Fab | ||
| - | **[[7fab]], [[1mco]], [[3na9]], [[3lrs]], [[3mme]], [[3hi5]], [[1vge]], [[3nfs]], [[1ad0]], [[3w9d]], [[4nm4]], [[8fab]], [[1opg]], [[4fnl]], [[4fqh]], [[6n32]], [[1aqk]], [[2hff]], [[2agj]], [[3hc0]], [[3g6a]], [[3dgg]], [[3dif]], [[1b2w]], [[3eyo]], [[3eyq]], [[2aj3]], [[3fzu]], [[3aaz]], [[3gje]], [[5fhb]], [[5fha]], [[5f6i]], [[5f6h]], [[5drw]], [[5d6c]], [[4py7]], [[4ptt]], [[4ob5]], [[5szf]], [[5chn]], [[4lkc]], [[4hie]], [[4gxv]], [[6be2]], [[6be4]], [[6cbj]], [[6dcv]], [[6dwc]], [[6foe]], [[6ghg]], [[6hkg]], [[6ias]], [[ | + | **[[7fab]], [[1mco]], [[3na9]], [[3lrs]], [[3mme]], [[3hi5]], [[1vge]], [[3nfs]], [[1ad0]], [[3w9d]], [[4nm4]], [[8fab]], [[1opg]], [[4fnl]], [[4fqh]], [[6n32]], [[1aqk]], [[2hff]], [[2agj]], [[3hc0]], [[3g6a]], [[3dgg]], [[3dif]], [[1b2w]], [[3eyo]], [[3eyq]], [[2aj3]], [[3fzu]], [[3aaz]], [[3gje]], [[5fhb]], [[5fha]], [[5f6i]], [[5f6h]], [[5drw]], [[5d6c]], [[4py7]], [[4ptt]], [[4ob5]], [[5szf]], [[5chn]], [[4lkc]], [[4hie]], [[4gxv]], [[6be2]], [[6be4]], [[6cbj]], [[6dcv]], [[6dwc]], [[6foe]], [[6ghg]], [[6hkg]], [[6ias]], [[7uen]], [[7uel]], [[7uem]], [[6obz]], [[6pzg]], [[6pzh]], [[6q19]], [[6q1a]], [[6q1e]], [[6q1g]], [[6q1j]], [[6q1k]], [[6qbc]], [[6qcu]], [[6u85]], [[6u9u]], [[6vi2]], [[6vrq]], [[6v4r]], [[6vpy]], [[6vtu]], [[6w5a]], [[6w5d]], [[6wiy]], [[6wj0]], [[6wla]], [[6xrj]], [[6z3k]], [[7aj6]], [[7arn]], [[7jkb]], [[7jz1]], [[7jz4]], [[7ke1]], [[7kfg]], [[7kgu]], [[7kx4]], [[7lud]], [[7lyv]], [[7lyw]], [[7m1c]], [[7mf7]], [[7mf8]], [[7mf9]], [[7mfa]], [[7n04]], [[7n07]], [[7oo2]], [[7ps3]], [[7qxc]], [[7qxd]], [[7qxe]], [[7re9]], [[7sen]], [[7tus]], [[7u04]], [[7u0k]], [[7vsu]], [[7vsw]], [[7y0g]] - hFab - human<br /> |
**[[3naa]], [[3nab]], [[3nac]], [[3ncj]], [[3o2v]], [[3hc3]], [[3hc4]], [[6uum]], [[6y1k]], [[6y1l]], [[6y1m]], [[6y1n]], [[7mfb]], [[7s8g]] - hFab (mutant)<br /> | **[[3naa]], [[3nab]], [[3nac]], [[3ncj]], [[3o2v]], [[3hc3]], [[3hc4]], [[6uum]], [[6y1k]], [[6y1l]], [[6y1m]], [[6y1n]], [[7mfb]], [[7s8g]] - hFab (mutant)<br /> | ||
**[[6b6z]], [[6dzn]], [[5vz1]], [[7rpt]] - hFab anti-ebola virus<br /> | **[[6b6z]], [[6dzn]], [[5vz1]], [[7rpt]] - hFab anti-ebola virus<br /> | ||
| Line 20: | Line 20: | ||
**[[6dl8]] - hFab anti-influenza<br /> | **[[6dl8]] - hFab anti-influenza<br /> | ||
**[[7kba]] - hFab anti-HCMV<br /> | **[[7kba]] - hFab anti-HCMV<br /> | ||
| - | **[[3i75 | + | **[[3i75]], [[1f4w]], [[1aif]], [[1ghf]], [[2z91]], [[1ind]], [[3bkc]], [[3bkm]], [[1iy0]], [[3pp3]], [[3pp4]], [[3okm]], [[2hkh]], [[1ay1]], [[1nbv]], [[1qbm]], [[1bbd]], [[1dsf]], [[1gpo]], [[1mnu]], [[1igf]], [[1for]], [[1k6q]], [[1bz7]], [[1dqd]], [[2ipt]], [[2iq9]], [[2iqa]], [[2w60]], [[2w9d]], [[3iu4]], [[1q9k]], [[1q9l]], [[1q9o]], [[2z4q]], [[1cl7]], [[1cr9]], [[1r24]], [[1gig]], [[1uyw]], [[1cgs]], [[2cgr]], [[1q0x]], [[1ibg]], [[3eo0]], [[2op4]], [[2q76]], [[2ojz]], [[2g60]], [[2dbl]], [[1dbj]], [[1dbk]], [[1dbm]], [[1dba]], [[1mrc]], [[2gcy]], [[1flr]], [[1uz6]], [[1rfd]], [[1t2q]], [[1ggb]], [[1ggc]], [[1bm3]], [[2eh7]], [[2fat]], [[3cfc]], [[1fl3]], [[3cfe]], [[4j1u]], [[4gq9]], [[3qg7]], [[3rvt]], [[3s62]], [[4gay]], [[5mx3]], [[5l88]], [[5i66]], [[5cma]], [[5az2]], [[4z0b]], [[4qth]], [[5vzr]], [[5lgh]], [[5l9d]], [[5l7x]], [[4lci]], [[4k23]], [[6hgu]], [[6ks2]], [[6p79]], [[6qnk]], [[6shg]], [[6ug7]], [[6ug8]], [[6uga]], [[6ugd]], [[6vl8]], [[6vl9]], [[6w4v]], [[6x5e]], [[6xuk]], [[6z7x]], [[7bg1]], [[7c95]], [[7f2s]], [[7fgk]], [[7nx2]], [[7sd2]], [[7t0f]], [[7t0g]], [[7t0h]], [[7t0k]], [[7t0i]], [[7t0j]], [[7te4]], [[7tuh]], [[7v3q]] - mFab – mouse<br /> |
**[[3eot]], [[2d03]], [[3esv]], [[3et9]] – mFab (mutant)<br /> | **[[3eot]], [[2d03]], [[3esv]], [[3et9]] – mFab (mutant)<br /> | ||
**[[3iy2]], [[3iy3]], [[3iy4]], [[3iy5]], [[3iy6]], [[3iy7]] - mFab – Cryo EM<br /> | **[[3iy2]], [[3iy3]], [[3iy4]], [[3iy5]], [[3iy6]], [[3iy7]] - mFab – Cryo EM<br /> | ||
| Line 104: | Line 104: | ||
**[[6cwd]] – rscFv + hepatitis B capsid<br /> | **[[6cwd]] – rscFv + hepatitis B capsid<br /> | ||
**[[5nph]], [[6bzu]], [[6bzv]], [[6bzw]], [[6bzy]] – mFab + hepatitis C virus peptide <br /> | **[[5nph]], [[6bzu]], [[6bzv]], [[6bzw]], [[6bzy]] – mFab + hepatitis C virus peptide <br /> | ||
| - | |||
*Human Fab: small molecule complex | *Human Fab: small molecule complex | ||
| Line 380: | Line 379: | ||
**[[7t8w]] – hFab + RSV glycoprotein <br /> | **[[7t8w]] – hFab + RSV glycoprotein <br /> | ||
**[[6mjz]] – hFab + respirovirus fusion protein<br /> | **[[6mjz]] – hFab + respirovirus fusion protein<br /> | ||
| - | |||
**[[4dag]], [[7sem]] – hFab + metapneumovirus glycoprotein F0<br /> | **[[4dag]], [[7sem]] – hFab + metapneumovirus glycoprotein F0<br /> | ||
**[[7tl0]], [[8cw9]] – hFab + metapneumovirus glycoprotein F0 – Cryo EM<br /> | **[[7tl0]], [[8cw9]] – hFab + metapneumovirus glycoprotein F0 – Cryo EM<br /> | ||
| Line 457: | Line 455: | ||
**[[4qww]] - mFab + acetylcholinesterase <br /> | **[[4qww]] - mFab + acetylcholinesterase <br /> | ||
**[[4qti]] – mFab + urokinase-type plasminogen activator <br /> | **[[4qti]] – mFab + urokinase-type plasminogen activator <br /> | ||
| - | **[[ | + | **[[5vco]] – mFab + peptidase<br /> |
**[[4p3d]], [[4p3c]] – mFab + metalloproteinase 14<br /> | **[[4p3d]], [[4p3c]] – mFab + metalloproteinase 14<br /> | ||
**[[4ong]], [[4onf]] - mFab + amyloid-β A4 protein<br /> | **[[4ong]], [[4onf]] - mFab + amyloid-β A4 protein<br /> | ||
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**[[3mac]], [[3ma9]], [[6fy1]] – hFab anti-HIV 8062 + transmembrane glycoprotein<br /> | **[[3mac]], [[3ma9]], [[6fy1]] – hFab anti-HIV 8062 + transmembrane glycoprotein<br /> | ||
| - | **[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]], [[5te4]], [[5fyl]], [[5f9w]], [[5f96]], [[5f6j]], [[4ywg]], [[4ye4]], [[4ydl]], [[4ydk]], [[4ydj]], [[4ydi]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[4rwy]], [[4rfn]], [[5w4l]], [[ | + | **[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]], [[5te4]], [[5fyl]], [[5f9w]], [[5f96]], [[5f6j]], [[4ywg]], [[4ye4]], [[4ydl]], [[4ydk]], [[4ydj]], [[4ydi]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[4rwy]], [[4rfn]], [[5w4l]], [[6w4m]], [[6bck]], [[6bf4]], [[6d2p]], [[6db5]], [[6oej]], [[6ofi]], [[7klc]], [[7rdw]] - hFab anti-HIV + gp120 core<br /> |
**[[6b0n]] - hFab anti-HIV + gp140<br /> | **[[6b0n]] - hFab anti-HIV + gp140<br /> | ||
**[[5v7j]], [[4j6r]] - hFab anti-HIV + gp160<br /> | **[[5v7j]], [[4j6r]] - hFab anti-HIV + gp160<br /> | ||
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**[[6cez]], [[6p65]], [[6vo0]] – rFab anti-HIV + HIV protein – Cryo EM<br /> | **[[6cez]], [[6p65]], [[6vo0]] – rFab anti-HIV + HIV protein – Cryo EM<br /> | ||
**[[5dhz]], [[5dhy]], [[5dhx]], [[5dhv]], [[6cbp]], [[6nnf]] – hscFv anti-HIV + HIV protein<br /> | **[[5dhz]], [[5dhy]], [[5dhx]], [[5dhv]], [[6cbp]], [[6nnf]] – hscFv anti-HIV + HIV protein<br /> | ||
| - | **[[3rjq], [[7r73]], [[7r74]], [[7ri1]], [[7ri2]] – LgVHH anti-HIV + gp120<br /> | + | **[[3rjq]], [[7r73]], [[7r74]], [[7ri1]], [[7ri2]] – LgVHH anti-HIV + gp120<br /> |
**[[7lpn]] – LgVHH anti-HIV + gp160 + gp41<br /> | **[[7lpn]] – LgVHH anti-HIV + gp160 + gp41<br /> | ||
**[[2xt1]], [[2xxm]] – ViVHH anti-HIV + HIV capsid<br /> | **[[2xt1]], [[2xxm]] – ViVHH anti-HIV + HIV capsid<br /> | ||
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**[[6pis]] – Fab + TRAAK – Cricetulus migratorius<br /> | **[[6pis]] – Fab + TRAAK – Cricetulus migratorius<br /> | ||
**[[7y7m]], [[7yms]], [[7yrf]], [[7yrh]] – Fab + coxsackievirus proteins – Cryo EM<br /> | **[[7y7m]], [[7yms]], [[7yrf]], [[7yrh]] – Fab + coxsackievirus proteins – Cryo EM<br /> | ||
| - | |||
*Human Fab: protein higher complexes | *Human Fab: protein higher complexes | ||
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**[[6gff]] – mFab + TGF + GARPIN<br /> | **[[6gff]] – mFab + TGF + GARPIN<br /> | ||
**[[7kpb]] – mFab + TNF + TNFR<br /> | **[[7kpb]] – mFab + TNF + TNFR<br /> | ||
| - | **[[7df9], [[7dfa]], [[7dfb]], [[7dfc | + | **[[7df9]], [[7dfa]], [[7dfb]], [[7dfc]] – mFab + arrestin + arrestin receptor<br /> |
*Full Immunoglobulin | *Full Immunoglobulin | ||
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**[[6ehy]], [[6ehv]], [[6ehw]], [[6ehx]], [[5c2b]], [[5wym]], [[1x9q]], [[2a9m]], [[3kdm]], [[4buh]], [[3u6r]], [[3auv]], [[6qb9]], [[6qf9]], [[6vrp]], [[7ah1]] – hscFv <br /> | **[[6ehy]], [[6ehv]], [[6ehw]], [[6ehx]], [[5c2b]], [[5wym]], [[1x9q]], [[2a9m]], [[3kdm]], [[4buh]], [[3u6r]], [[3auv]], [[6qb9]], [[6qf9]], [[6vrp]], [[7ah1]] – hscFv <br /> | ||
| - | **[[4x4x]], [[ | + | **[[4x4x]], [[6dn0]], [[2a9n]], [[6vun]], [[6vuo]], [[6vup]], [[7kbm]], [[7kbo]], [[7kpb]] – hscFv (mutant)<br /> |
**[[6ffj]] – hscFv anti-tumor<br /> | **[[6ffj]] – hscFv anti-tumor<br /> | ||
**[[6uup]], [[6uy3]] – cscFv - camel <br /> | **[[6uup]], [[6uy3]] – cscFv - camel <br /> | ||
**[[6pil]], [[6psc]] – rscFv <br /> | **[[6pil]], [[6psc]] – rscFv <br /> | ||
| - | **[[4h0g]], [[4nkd]], [[4nkm]], [[4nko]], [[3nn8]], [[3bd3]], [[3bd4]], [[3bd5]], [[2gjj]], [[5b3n]], [[4laq]], [[4gqp]], [[3umt]], [[6s2i]], [[6tnp]], [[7aql]] – mscFv <br /> | + | **[[1h8n]], [[1lmk]], [[1nqb]],[[4h0g]], [[4nkd]], [[4nkm]], [[4nko]], [[3nn8]], [[3bd3]], [[3bd4]], [[3bd5]], [[2gjj]], [[5b3n]], [[4laq]], [[4gqp]], [[3umt]], [[6s2i]], [[6tnp]], [[7aql]], [[7eq3]] – mscFv <br /> |
**[[1p4i]] – mscFv (mutant)<br /> | **[[1p4i]] – mscFv (mutant)<br /> | ||
**[[4p49]], [[4p48]], [[4ouo]], [[5vf6]] – scFv - chicken<br /> | **[[4p49]], [[4p48]], [[4ouo]], [[5vf6]] – scFv - chicken<br /> | ||
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**[[5jz7]] – hscFv + NGF<br /> | **[[5jz7]] – hscFv + NGF<br /> | ||
**[[4kv5]] – hscFv + TGF<br /> | **[[4kv5]] – hscFv + TGF<br /> | ||
| + | **[[5iwl]] – hscFv + CD47<br /> | ||
**[[6tou]] – hscFv + rabies glycoprotein<br /> | **[[6tou]] – hscFv + rabies glycoprotein<br /> | ||
**[[6ikm]] – hscFv + polyamine transport protein<br /> | **[[6ikm]] – hscFv + polyamine transport protein<br /> | ||
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**[[1dzb]], [[2znx]] – mscFv + lysozyme<br /> | **[[1dzb]], [[2znx]] – mscFv + lysozyme<br /> | ||
**[[1a14]], [[1nmc]] – mscFv + neuraminidase<br /> | **[[1a14]], [[1nmc]] – mscFv + neuraminidase<br /> | ||
| + | **[[5gs2]] – mscFv + MBP + repebody<br /> | ||
**[[1fo0]], [[1kj2]], [[1nam]] – mscFv + TCR + MHC + peptide<br /> | **[[1fo0]], [[1kj2]], [[1nam]] – mscFv + TCR + MHC + peptide<br /> | ||
**[[7k5x]], [[7k5y]], [[7k60]], [[7k61]], [[7k63]] - mscFv + human nucleosome – Cryo EM<br /> | **[[7k5x]], [[7k5y]], [[7k60]], [[7k61]], [[7k63]] - mscFv + human nucleosome – Cryo EM<br /> | ||
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**[[3p0g]], [[4lde]], [[4ldl]], [[4ldo]], [[6mxt]], [[7bu7]] – LgVHH + adrenergic receptor<br /> | **[[3p0g]], [[4lde]], [[4ldl]], [[4ldo]], [[6mxt]], [[7bu7]] – LgVHH + adrenergic receptor<br /> | ||
**[[4n1h]], [[4m3k]], [[5lwf]] – LgVHH + beta-lactamase<br /> | **[[4n1h]], [[4m3k]], [[5lwf]] – LgVHH + beta-lactamase<br /> | ||
| - | ** | + | **[[5m94]], [[5m95]] – LgVHH + metal cation transporter<br /> |
**[[5h8o]], [[6f2g]] – LgVHH + ASC<br /> | **[[5h8o]], [[6f2g]] – LgVHH + ASC<br /> | ||
**[[3k3q]] – LgVHH + Botox<br /> | **[[3k3q]] – LgVHH + Botox<br /> | ||
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**[[6gs4]] – LgVHH + DtpA<br /> | **[[6gs4]] – LgVHH + DtpA<br /> | ||
**[[6z1v]] – LgVHH + CD9<br /> | **[[6z1v]] – LgVHH + CD9<br /> | ||
| - | **[[ | + | **[[7anq]] - LgVHH + PCSK9 <br /> |
**[[7d4b]] - LgVHH + TNFRSF9 <br /> | **[[7d4b]] - LgVHH + TNFRSF9 <br /> | ||
**[[7nmu]] - LgVHH + platelet glycoprotein<br /> | **[[7nmu]] - LgVHH + platelet glycoprotein<br /> | ||
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*Diabody or single chain Fv | *Diabody or single chain Fv | ||
| - | **[[5fcs]], [[5grv]], [[5grw]], [[5grx]], [[5gry]], [[5grz]], [[5gs1 | + | **[[5fcs]], [[5grv]], [[5grw]], [[5grx]], [[5gry]], [[5grz]], [[5gs1]] – hDiab<br /> |
| - | + | ||
**[[4y5v]], [[4y5x]], [[4y5y]] – hDiab + EpoR<br /> | **[[4y5v]], [[4y5x]], [[4y5y]] – hDiab + EpoR<br /> | ||
**[[5gru]] – hDiab + MBP<br /> | **[[5gru]] – hDiab + MBP<br /> | ||
| - | **[[5iwl]] – hDiab + CD47<br /> | ||
| - | **[[6vug]] – hDiab + Hiv reverse transcriptase + DNA<br /> | ||
| - | **[[1h8n]], [[1lmk]], [[1nqb]], [[7eq3]] – mDiab<br /> | ||
| - | **[[5gs2]] – mDiab + MBP + repebody<br /> | ||
**[[5gs0]] – hDiab + TLR3<br /> | **[[5gs0]] – hDiab + TLR3<br /> | ||
| + | **[[6vug]] – hDiab + Hiv reverse transcriptase + DNA<br /> | ||
| + | |||
| + | *Antibody VH domain (residues 1-121) | ||
| + | |||
| + | **[[1t2j]], [[3b9v]], [[3qyc]], [[7omn]], [[7ooi]] – hVH <br /> | ||
| + | **[[1vhp]] – hVH - NMR<br /> | ||
| + | **[[7d6y]], [[7d8b]], [[7f07]], [[7xtp]] – hVH + EIF4E<br /> | ||
| + | **[[4u3x]] – hVH + lysozyme<br /> | ||
| + | **[[7dv4]] – hVH + CTLA-4<br /> | ||
| + | **[[5fv2]] – hVH + VEGF<br /> | ||
| + | **[[8di5]] – hVH + SARS spike glycoprotein – Cryo EM<br /> | ||
| + | **[[1nqb]] – mVH <br /> | ||
| + | **[[4qgy]], [[4qlr]] – LgVH <br /> | ||
}} | }} | ||
[[Category: Topic Page]] | [[Category: Topic Page]] | ||
Current revision
Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.
Broadly neutralizing Fab and Neutralizing Fab are anti-HIV Fab.
Lama antibodies or nanobodies or camelid or VHH are natural single-domain antibodies containing just the heavy chain.
scFv is a single chain variable fragment in a fusion protein of the variable regions of the heavy and light chains of immunoglobulin.
3D structures of Antibody
Updated on 11-March-2023
