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Galactosidase 3D structures

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(New page: == 3D Structures of Galactosidase == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *α-Galactosidase **3hg2,...)
Current revision (19:34, 11 March 2023) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 8: Line 8:
**[[3hg2]], [[3gxn]], [[1r46]], [[1r47]], [[3s5y]], [[3s5z]] – hAgal A - human<br />
**[[3hg2]], [[3gxn]], [[1r46]], [[1r47]], [[3s5y]], [[3s5z]] – hAgal A - human<br />
**[[3lx9]], [[3lxa]], [[3lxb]], [[3lxc]], [[3tv8]] - hAgal A (mutant) <br />
**[[3lx9]], [[3lxa]], [[3lxb]], [[3lxc]], [[3tv8]] - hAgal A (mutant) <br />
 +
**[[3h53]] - hAgal B (mutant)<br />
 +
**[[1uas]] – Agal – rice<br />
**[[3lrk]] – yAgal 1 (mutant) – yeast<br />
**[[3lrk]] – yAgal 1 (mutant) – yeast<br />
**[[3lrl]], [[3lrm]] – yAgal 1 (mutant) + polysaccharide<br />
**[[3lrl]], [[3lrm]] – yAgal 1 (mutant) + polysaccharide<br />
**[[1zy9]], [[5m0x]] – TmAgal – ''Thermotoga maritima''<br />
**[[1zy9]], [[5m0x]] – TmAgal – ''Thermotoga maritima''<br />
-
**[[3h53]] - hAgal B (mutant)<br />
 
**[[3a24]] – BtAgal – ''Bacterioides thetaiotamicron''<br />
**[[3a24]] – BtAgal – ''Bacterioides thetaiotamicron''<br />
**[[3a5v]] – Agal I – ''Mortierella vinacea''<br />
**[[3a5v]] – Agal I – ''Mortierella vinacea''<br />
**[[3mi6]] – Agal – ''Lactobacillus brevis''<br />
**[[3mi6]] – Agal – ''Lactobacillus brevis''<br />
**[[1szn]] – HjAgal – ''Hypocrea jecorina''<br />
**[[1szn]] – HjAgal – ''Hypocrea jecorina''<br />
-
**[[1uas]] – Agal – rice<br />
 
**[[2xn0]], [[2xn1]] – LaAgal – ''Lactobacillus acidophilus''<br />
**[[2xn0]], [[2xn1]] – LaAgal – ''Lactobacillus acidophilus''<br />
-
**[[4fnp]], [[4ojy]] – GsAgal (mutant) – ''Geobacillus stearothermophilus''<br />
+
**[[4fnp]] – GsAgal (mutant) – ''Geobacillus stearothermophilus''<br />
**[[4fnq]], [[4fnr]], [[4oif]] – GsAgal<br />
**[[4fnq]], [[4fnr]], [[4oif]] – GsAgal<br />
**[[4xpo]] - PsBgal – ''Pedobacter saltans'' <br />
**[[4xpo]] - PsBgal – ''Pedobacter saltans'' <br />
**[[4xpr]] - PsAgal (mutant)<br />
**[[4xpr]] - PsAgal (mutant)<br />
**[[6f4c]] - Agal – ''Nicotiana benthamiana''<br />
**[[6f4c]] - Agal – ''Nicotiana benthamiana''<br />
 +
**[[6jhp]] - Agal – ''Paecilomyces''<br />
 +
**[[6lcj]] - TtAgal – ''Thermus thermophilus''<br />
 +
**[[6phu]] – SpAgal – ''Streptococcus pneumoniae<''br />
 +
**[[6y2k]] - Agal – ''Marinomonas''<br />
*''α-galactosidase binary complex''
*''α-galactosidase binary complex''
Line 34: Line 38:
**[[3gxt]] – hAgal A + imino sugar<br />
**[[3gxt]] – hAgal A + imino sugar<br />
**[[4nxs]] - hAgal + jirimycin derivative<br />
**[[4nxs]] - hAgal + jirimycin derivative<br />
 +
**[[6ibk]], [[6ibm]], [[6ibr]], [[6ibt]] - hAgal A + trisaccharide + cyclosulfamidate<br />
 +
**[[7exq]], [[7exr]] - Agal + saccharide – ''Arabidopsis thaliana''<br />
**[[1t0o]] – HjAgal + galactose<br />
**[[1t0o]] – HjAgal + galactose<br />
**[[2xn2]] - LaAgal + galactose<br />
**[[2xn2]] - LaAgal + galactose<br />
Line 44: Line 50:
**[[5m12]], [[5m16]], [[5m1i]], [[6gx8]], [[6gwg]], [[6gvd]] - TmAgal + sugar<br />
**[[5m12]], [[5m16]], [[5m1i]], [[6gx8]], [[6gwg]], [[6gvd]] - TmAgal + sugar<br />
**[[6gwf]], [[6gta]] - TmAgal (mutant) + sugar<br />
**[[6gwf]], [[6gta]] - TmAgal (mutant) + sugar<br />
 +
**[[6lck]], [[6lcl]] - TtAgal + saccharide<br />
 +
**[[6phv]] - SpAgal + galactopyranoside derivative<br />
 +
**[[6phw]], [[6phx]], [[6phy]], [[6pi0]] - SpAgal (mutant) + oligosaccharide<br />
*β-Galactosidase
*β-Galactosidase
 +
**[[3w5f]] – toBgal – tomato<br />
 +
**[[5iaz]] - rBgal C-terminal - NMR<br />
**[[3og2]] – TrBgal – ''Trichoderma reesei''<br />
**[[3og2]] – TrBgal – ''Trichoderma reesei''<br />
-
**[[1hn1]], [[1dp0]], [[1f4a]], [[1f4h]], [[4v41]], [[4v40]], [[4ttg]] - EcBgal - Escherichia coli<br />
+
**[[1hn1]], [[1dp0]], [[1f4a]], [[1f4h]], [[4v41]], [[4v40]], [[4ttg]], [[6drv]] - EcBgal - ''Escherichia coli''<br />
-
**[[3j7h]], [[6cvm]] – EcBgal – cryo EM<br />
+
**[[3muy]], [[3i3e]], [[3iap]], [[3iaq]], [[3dym]], [[3dyp]], [[1px3]], [[3sep]], [[3t0a]], [[3t2o]], [[3vd3]], [[3vd5]], [[3vda]], [[4duv]] – EcBgal (mutant)<br />
-
**[[3dec]], [[3d3a]], [[3bga]], [[5mt2]], [[5mui]], [[5muj]] – BtBgal<br />
+
**[[3j7h]], [[6cvm]], [[6drv]], [[6x1q]] – EcBgal – cryo EM<br />
-
**[[6etz]], [[6h1p]] - ArBgal – ''Arthrobacter''<br />
+
**[[3dec]], [[3d3a]], [[3bga]], [[5mt2]], [[5mui]], [[5muj]], [[6euf]], [[6euj]] – BtBgal<br />
-
**[[1yq2]] - ArBgal (mutant)<br />
+
**[[6etz]], [[6h1p]], [[6zjv]] - ArBgal – ''Arthrobacter''<br />
 +
**[[1yq2]], [[6se8]], [[6zjp]] - ArBgal (mutant)<br />
**[[1uwi]], [[4eam]], [[5i3d]] - SsBgal (mutant) - ''Sulfolobus solfataricus''<br />
**[[1uwi]], [[4eam]], [[5i3d]] - SsBgal (mutant) - ''Sulfolobus solfataricus''<br />
**[[1uwq]], [[1gow]] – SsBgal<br />
**[[1uwq]], [[1gow]] – SsBgal<br />
**[[1kwg]] – TtBgal – ''Thermus thermophilus''<br />
**[[1kwg]] – TtBgal – ''Thermus thermophilus''<br />
**[[1tg7]] – PeBgal – ''Penicillium''<br />
**[[1tg7]] – PeBgal – ''Penicillium''<br />
-
**[[3tts]], [[4mad]] – BcBgal – ''Bacillus circulans''<br />
+
**[[3tts]], [[4mad]], [[7cwi]] – BcBgal – ''Bacillus circulans''<br />
**[[4ypj]] - BcBgal (mutant) <br />
**[[4ypj]] - BcBgal (mutant) <br />
**[[4ha3]], [[4ha4]] – Bgal – ''Acidilobus saccharovorans''<br />
**[[4ha3]], [[4ha4]] – Bgal – ''Acidilobus saccharovorans''<br />
-
**[[3w5f]] – toBgal – tomato<br />
+
**[[3wq8]], [[6jow]] – Bgal – ''Pyrococcus furiosus''<br />
-
**[[3wq8]] – Bgal – ''Pyrococcus furiosus''<br />
+
**[[4cu6]], [[4cu8]] – SpBgal catalytic module residues 137-985– ''Streptococcus pneumoniae''<br />
-
**[[4cu6]] – SpBgal catalytic module residues 137-985– ''Streptococcus pneumoniae''<br />
+
**[[4cu9]] – SpBgal carbohydrate-binding module II residues 1822-1998 <br />
**[[4cu9]] – SpBgal carbohydrate-binding module II residues 1822-1998 <br />
**[[4cua]] – SpBgal carbohydrate-binding module I residues 1463-1645 <br />
**[[4cua]] – SpBgal carbohydrate-binding module I residues 1463-1645 <br />
Line 69: Line 80:
**[[5vym]] - Bgal – ''Bifidobacterium adolescentis''<br />
**[[5vym]] - Bgal – ''Bifidobacterium adolescentis''<br />
**[[5nav]], [[5naq]] - Bgal – ''Lactobacillus plantarum''<br />
**[[5nav]], [[5naq]] - Bgal – ''Lactobacillus plantarum''<br />
 +
**[[5yhs]] - BacBgal – ''Bacillus'' <br />
**[[3ob8]], [[3oba]] – Bgal – ''Kluyveromyces lactis''<br />
**[[3ob8]], [[3oba]] – Bgal – ''Kluyveromyces lactis''<br />
**[[5dfa]] - GsBgal (mutant) <br />
**[[5dfa]] - GsBgal (mutant) <br />
-
**[[5dmy]] - BbBgal – ''Bifidobacterium bifidum''<br />
+
**[[5dmy]], [[6quc]], [[7nit]] - BbBgal – ''Bifidobacterium bifidum''<br />
**[[5e9a]] - Bgal - ''Rahnella''<br />
**[[5e9a]] - Bgal - ''Rahnella''<br />
**[[5euv]] - ParBgal - ''Paracoccus''<br />
**[[5euv]] - ParBgal - ''Paracoccus''<br />
-
**[[5iaz]] - rBgal C-terminal - NMR<br />
+
**[[5ifp]] - AnBgal – ''Aspergillus niger''<br />
-
**[[5ifp]] - Bgal – ''Aspergillus niger''<br />
+
**[[6mvh]] - Bgal – ''Roseburia hominis''<br />
**[[6mvh]] - Bgal – ''Roseburia hominis''<br />
 +
**[[6hpd]] - Bgal – ''Formosa agariphila''<br />
 +
**[[6s6z]], [[6sd0]] - TmBgal – Cryo EM <br />
 +
**[[6lvw]] - Bgal – ''Halorubrum lacusprofundi''<br />
 +
**[[6u7i]] - FpBgal – ''Faecaibavterium prausnitzii''<br />
 +
**[[6u7j]] - Bgal – ''Clostridium''<br />
 +
**[[6m4e]] - Bgal – ''Hamamotoa singularis''<br />
 +
**[[6ld6]] - BdBgal – ''Bifidobacterium dentium''<br />
 +
**[[6ec6]], [[6jz1]] - RgBgal – ''Ruminococcus gnavus''<br />
 +
**[[7kmn]] - XcBgal – ''Xanthomonas citri'' <br />
 +
**[[4d1i]] - CjBgal – ''Cellvibrio japonicus''<br />
 +
**[[7f1n]] - Bgal - ''Thermofilum''<br />
 +
**[[7sf2]] - Bgal – ''Bacterioides cellulosilyticus''<br />
*''β-Galactosidase binary complex with galactose''
*''β-Galactosidase binary complex with galactose''
Line 82: Line 105:
**[[3thc]] - hBgal + galactose<br />
**[[3thc]] - hBgal + galactose<br />
**[[3wf3]] - hBgal + galactose + NAG<br />
**[[3wf3]] - hBgal + galactose + NAG<br />
-
**[[1xc6]] - PeBgal + galactose<br />
 
**[[3w5g]], [[6ik5]] - toBgal + galactose<br />
**[[3w5g]], [[6ik5]] - toBgal + galactose<br />
**[[6ik6]], [[6ik7]], [[6ik8]] - toBgal (mutant) + galactobiose<br />
**[[6ik6]], [[6ik7]], [[6ik8]] - toBgal (mutant) + galactobiose<br />
Line 91: Line 113:
**[[4iug]] - Bgal + galactose – ''Aspergillus oryzae''<br />
**[[4iug]] - Bgal + galactose – ''Aspergillus oryzae''<br />
**[[3tty]] - BcBgal + galactose<br />
**[[3tty]] - BcBgal + galactose<br />
-
**[[4cub]] – SpBgal carbohydrate-binding module I + galactose <br />
+
**[[4cub]], [[4e8c]], [[4e8d]] – SpBgal carbohydrate-binding module I + galactose <br />
**[[4cuc]] – SpBgal catalytic module (mutant) + galactose <br />
**[[4cuc]] – SpBgal catalytic module (mutant) + galactose <br />
**[[4uni]] - BaBgal + galactose <br />
**[[4uni]] - BaBgal + galactose <br />
**[[4uoz]] - BaBgal (mutant) + galactose <br />
**[[4uoz]] - BaBgal (mutant) + galactose <br />
-
**[[4ucf]], [[4uzs]] - BbBgal + galactose <br />
+
**[[4ucf]], [[4uzs]], [[6qub]], [[6qud]] - BbBgal + galactose <br />
**[[5ldr]] - ParBgal + galactose <br />
**[[5ldr]] - ParBgal + galactose <br />
**[[6eon]] - BtBgal + galactose <br />
**[[6eon]] - BtBgal + galactose <br />
 +
**[[1xc6]] - PeBgal + galactose<br />
 +
**[[6sed]] - ArBgal + galactose <br />
 +
**[[6zjq]], [[6zjs]], [[6zjw]] - ArBgal (mutant) + galactose <br />
 +
**[[6zju]] - ArBgal (mutant) + saccharose <br />
 +
**[[5yif]] - BacBgal (mutant) + galactose <br />
 +
**[[7kmo]] - XcBgal + galactose <br />
 +
**[[6eui]] - BtBgal + galactose<br />
*''β-Galactosidase other complexes''
*''β-Galactosidase other complexes''
Line 106: Line 135:
**[[3wf4]] - hBgal (mutant) + pyridine derivative<br />
**[[3wf4]] - hBgal (mutant) + pyridine derivative<br />
**[[3wf2]] - hBgal + piperidine derivative<br />
**[[3wf2]] - hBgal + piperidine derivative<br />
 +
**[[7kdv]] - Bgal + cathepsin A – mouse – Cryo EM<br />
 +
**[[7bzm]] - rBgal + glucoimidazole <br />
**[[3ogs]] - TrBgal + IPTG<br />
**[[3ogs]] - TrBgal + IPTG<br />
**[[3ogv]] – TrBgal + inhibitor<br />
**[[3ogv]] – TrBgal + inhibitor<br />
Line 118: Line 149:
**[[1jz6]] - EcBgal (mutant) + inhibitor<br />
**[[1jz6]] - EcBgal (mutant) + inhibitor<br />
**[[4duw]] - EcBgal (mutant) + allolactose<br />
**[[4duw]] - EcBgal (mutant) + allolactose<br />
 +
**[[6tsk]] - EcBgal + ribose – Cryo EM<br />
**[[4dux]] - EcBgal (mutant) + ribose<br />
**[[4dux]] - EcBgal (mutant) + ribose<br />
 +
**[[6tte]] - EcBgal + galactopyranoside derivative – Cryo EM<br />
 +
**[[6tsh]] - EcBgal + jirimycin derivative – Cryo EM<br />
 +
**[[6kuz]], [[7brs]], [[7btk]] - EcBgal (mutant) + probe<br />
 +
**[[6leg]], [[6lej]], [[6lel]], [[6lem]] - EcBgal + Gauche drug<br />
**[[4ckd]] – EcBgal + antibody<br />
**[[4ckd]] – EcBgal + antibody<br />
-
**[[4cu7]] - SpBgal catalytic module + galacto-isofagomine<br />
+
**[[4cu7]] - SpBgal catalytic module + Gaucher drug<br />
 +
**[[6nzg]] - BuBgal + aziridine derivative – ''Bacterioides uniformis''<br />
 +
**[[6seb]], [[6sec]] - ArBgal + galactopyranoside derivative<br />
 +
**[[6se9]], [[6sea]] - ArBgal (mutant) + lactose<br />
 +
**[[6zjx]] - ArBgal (mutant) + saccharose<br />
 +
**[[6zjr]], [[6zjt]] - ArBgal (mutant) + lactulose<br />
 +
**[[7cwd]] - BcBgal + disaccharide<br />
 +
**[[6ld0]], [[6ldb]], [[6ldc]], [[6ldd]] - BdBgal + Gauche drug<br />
 +
**[[6jz2]], [[6jz6]], [[6jz7]] - RgBgal + Gauche drug <br />
 +
**[[6jz4]], [[6jz8]] - RgBgal + glucaro lactone<br />
 +
**[[5mgc]], [[5mgd]] - RgBgal (mutant) + disaccharise <br />
 +
**[[6jz3]] - RgBgal + drug <br />
 +
**[[6mvf]] - FpBgal + FMN <br />
 +
**[[6d4o]] - Bgal + glucuronic acid derivative – ''Lachnospira eligens''<br />
 +
**[[6euh]] - BtBgal + drug <br />
 +
**[[6eug]] - BtBgal + galactoimidazole<br />
 +
**[[7zvo]] - BtBgal + Ser + Ala <br />
 +
**[[5jaw]], [[6tbf]], [[6tbg]], [[6tbh]], [[6tbi]], [[6tbj]], [[6tbk]] - CjBgal + inhibitor<br />
 +
**[[4d1j]] - CjBgal + drug <br />
 +
**[[5ift]], [[5ihr]], [[5juv]] - AnBgal (mutant) + saccharide<br />
*Endo-1,4-β-galactosidase
*Endo-1,4-β-galactosidase
Line 128: Line 183:
**[[2ygl]], [[2ygm]] – SpEbgal blood group A & B cleaving <br />
**[[2ygl]], [[2ygm]] – SpEbgal blood group A & B cleaving <br />
**[[4bf7]] – Ebgal – ''Emericella nidulans''<br />
**[[4bf7]] – Ebgal – ''Emericella nidulans''<br />
 +
**[[7pmo]] – Rggal <br />
 +
**[[7q1w]], [[7q20]] – Rggal (mutant) + polysaccharide<br />
*3,6-anhydro-α-L-galactosidase
*3,6-anhydro-α-L-galactosidase
**[[3p2n]], [[5opq]] – AAgal – ''Zobellia galactanivorans''<br />
**[[3p2n]], [[5opq]] – AAgal – ''Zobellia galactanivorans''<br />
-
**[[4ak5]] – BpAAgal – ''Bacterioides plebeius''<br />
+
**[[4ak5]], [[7ljj]] – BpAAgal – ''Bacterioides plebeius''<br />
**[[4ak6]] – BpAAgal (mutant)<br />
**[[4ak6]] – BpAAgal (mutant)<br />
-
**[[4ak7]] – BpAAgal (mutant) + polysaccharide<br />
+
**[[4ak7]], [[7lnp]] – BpAAgal (mutant) + polysaccharide<br />
 +
**[[7lk7]] – BpAAgal + galactose<br />
*6-phospho-β-D-galactosidase
*6-phospho-β-D-galactosidase
**[[2pbg]], [[3pbg]], [[4pbg]], [[1pbg]] – Pgal (mutant) – ''Lactococcus lacti''<br />
**[[2pbg]], [[3pbg]], [[4pbg]], [[1pbg]] – Pgal (mutant) – ''Lactococcus lacti''<br />
-
**[[2v4v]] – gal GH59 – ''Clostridium cellulolyticum''
+
**[[2v4v]] – gal GH59 – ''Clostridium cellulolyticum''<br />
 +
**[[4zep]] – GsPgal + phospho-glucose<br />
 +
**[[7m1r]] – Pgal – ''Bacillus licheiformis''<br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of Galactosidase

Updated on 11-March-2023

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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