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2n4q
From Proteopedia
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==Solution NMR structure of CBX8 in complex with AF9 (CBX8-AF9)== | ==Solution NMR structure of CBX8 in complex with AF9 (CBX8-AF9)== | ||
| - | <StructureSection load='2n4q' size='340' side='right'caption='[[2n4q | + | <StructureSection load='2n4q' size='340' side='right'caption='[[2n4q]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2n4q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2n4q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N4Q FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n4q OCA], [https://pdbe.org/2n4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n4q RCSB], [https://www.ebi.ac.uk/pdbsum/2n4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n4q ProSAT]</span></td></tr> |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n4q OCA], [https://pdbe.org/2n4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n4q RCSB], [https://www.ebi.ac.uk/pdbsum/2n4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n4q ProSAT]</span></td></tr> | + | |
</table> | </table> | ||
| - | == Disease == | ||
| - | [[https://www.uniprot.org/uniprot/AF9_HUMAN AF9_HUMAN]] A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9;11)(p22;q23) with KMT2A/MLL1. The result is a rogue activator protein. | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/CBX8_HUMAN CBX8_HUMAN] | |
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bushweller | + | [[Category: Bushweller JH]] |
| - | [[Category: Kuntimaddi | + | [[Category: Kuntimaddi A]] |
| - | [[Category: Leach | + | [[Category: Leach BI]] |
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Revision as of 10:18, 15 March 2023
Solution NMR structure of CBX8 in complex with AF9 (CBX8-AF9)
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