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2na1
From Proteopedia
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==ULD complex== | ==ULD complex== | ||
| - | <StructureSection load='2na1' size='340' side='right' caption='[[2na1 | + | <StructureSection load='2na1' size='340' side='right'caption='[[2na1]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2na1]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2na1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NA1 FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2na1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2na1 OCA], [https://pdbe.org/2na1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2na1 RCSB], [https://www.ebi.ac.uk/pdbsum/2na1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2na1 ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHC2_MOUSE PHC2_MOUSE] Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.<ref>PMID:16024804</ref> [https://www.uniprot.org/uniprot/BMI1_HUMAN BMI1_HUMAN] Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.<ref>PMID:16359901</ref> <ref>PMID:16882984</ref> <ref>PMID:16714294</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 2na1" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2na1" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Polycomb complex proteins 3D structures|Polycomb complex proteins 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: | + | [[Category: Cho H]] |
| - | [[Category: | + | [[Category: Cierpicki T]] |
| - | [[Category: | + | [[Category: Gray F]] |
| - | + | ||
Current revision
ULD complex
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