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2oxv

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<StructureSection load='2oxv' size='340' side='right'caption='[[2oxv]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='2oxv' size='340' side='right'caption='[[2oxv]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2oxv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OXV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2oxv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OXV FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ecoRIR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxv OCA], [https://pdbe.org/2oxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oxv RCSB], [https://www.ebi.ac.uk/pdbsum/2oxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oxv ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxv OCA], [https://pdbe.org/2oxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oxv RCSB], [https://www.ebi.ac.uk/pdbsum/2oxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oxv ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/T2E1_ECOLX T2E1_ECOLX]] Recognizes the double-stranded sequence GAATTC and cleaves after G-1.
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[https://www.uniprot.org/uniprot/T2E1_ECOLX T2E1_ECOLX] Recognizes the double-stranded sequence GAATTC and cleaves after G-1.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Type II site-specific deoxyribonuclease]]
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[[Category: Jen-Jacobson L]]
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[[Category: Jen-Jacobson, L]]
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[[Category: Rosenberg JM]]
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[[Category: Rosenberg, J M]]
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[[Category: Sapienza PJ]]
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[[Category: Sapienza, P J]]
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[[Category: Ecori]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Promiscuous mutant]]
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[[Category: Protein-dna interaction]]
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[[Category: Relaxed specificity mutant]]
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[[Category: Type ii restriction endonuclease]]
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Revision as of 10:29, 15 March 2023

Structure of the A138T promiscuous mutant of the EcoRI restriction endonuclease bound to its cognate recognition site.

PDB ID 2oxv

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OCA

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