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4u4l
From Proteopedia
(Difference between revisions)
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<StructureSection load='4u4l' size='340' side='right'caption='[[4u4l]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='4u4l' size='340' side='right'caption='[[4u4l]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4u4l]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4u4l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U4L FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3C7:(3R,5R,7AS)-5-(SULFANYLMETHYL)TETRAHYDRO[1,3]THIAZOLO[4,3-B][1,3]THIAZOLE-3-CARBOXYLIC+ACID'>3C7</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3C7:(3R,5R,7AS)-5-(SULFANYLMETHYL)TETRAHYDRO[1,3]THIAZOLO[4,3-B][1,3]THIAZOLE-3-CARBOXYLIC+ACID'>3C7</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u4l OCA], [https://pdbe.org/4u4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u4l RCSB], [https://www.ebi.ac.uk/pdbsum/4u4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u4l ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Klebsiella pneumoniae]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Hinchliffe | + | [[Category: Hinchliffe P]] |
| - | [[Category: Kosmopoulou | + | [[Category: Kosmopoulou M]] |
| - | [[Category: Spencer | + | [[Category: Spencer J]] |
| - | + | ||
Revision as of 08:01, 22 March 2023
Crystal structure of the metallo-beta-lactamase NDM-1 in complex with a bisthiazolidine inhibitor
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