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4wq3

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<StructureSection load='4wq3' size='340' side='right'caption='[[4wq3]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
<StructureSection load='4wq3' size='340' side='right'caption='[[4wq3]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4wq3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQ3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4wq3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WQ3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3SU:(2Z)-3-(6-BROMO-1H-INDOL-3-YL)-2-SULFANYLPROP-2-ENOIC+ACID'>3SU</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3SU:(2Z)-3-(6-BROMO-1H-INDOL-3-YL)-2-SULFANYLPROP-2-ENOIC+ACID'>3SU</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wq3 OCA], [http://pdbe.org/4wq3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wq3 RCSB], [http://www.ebi.ac.uk/pdbsum/4wq3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wq3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wq3 OCA], [https://pdbe.org/4wq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wq3 RCSB], [https://www.ebi.ac.uk/pdbsum/4wq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wq3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CPNS1_HUMAN CPNS1_HUMAN]] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
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[https://www.uniprot.org/uniprot/CPNS1_HUMAN CPNS1_HUMAN] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Adams, S E]]
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[[Category: Adams SE]]
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[[Category: Allemann, R K]]
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[[Category: Allemann RK]]
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[[Category: Hallett, M B]]
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[[Category: Hallett MB]]
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[[Category: Miller, D J]]
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[[Category: Miller DJ]]
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[[Category: Rizkallah, P J]]
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[[Category: Rizkallah PJ]]
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[[Category: Robinson, E J]]
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[[Category: Robinson EJ]]
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[[Category: Calcium binding domain]]
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[[Category: Cysteine protease]]
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[[Category: Domain vi]]
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[[Category: Hydrolase]]
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[[Category: Mercaptoacrylic acid]]
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Revision as of 07:20, 7 April 2023

Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-bromoindol-3-yl)acrylic acid) bound

PDB ID 4wq3

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