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4xdv

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<StructureSection load='4xdv' size='340' side='right'caption='[[4xdv]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='4xdv' size='340' side='right'caption='[[4xdv]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xdv]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XDV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XDV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xdv]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XDV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=40O:(1R,2R)-CYCLOHEXANE-1,2-DIOL'>40O</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=40O:(1R,2R)-CYCLOHEXANE-1,2-DIOL'>40O</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xbt|4xbt]], [[4xbx|4xbx]], [[4xby|4xby]], [[4xdw|4xdw]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xdv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xdv OCA], [https://pdbe.org/4xdv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xdv RCSB], [https://www.ebi.ac.uk/pdbsum/4xdv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xdv ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">limA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 "Mycobacterium erythropolis" Gray and Thornton 1928])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Limonene-1,2-epoxide_hydrolase Limonene-1,2-epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.8 3.3.2.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xdv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xdv OCA], [http://pdbe.org/4xdv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xdv RCSB], [http://www.ebi.ac.uk/pdbsum/4xdv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xdv ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LIMA_RHOER LIMA_RHOER]] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates.
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[https://www.uniprot.org/uniprot/LIMA_RHOER LIMA_RHOER] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Epoxide hydrolase|Epoxide hydrolase]]
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*[[Epoxide hydrolase 3D structures|Epoxide hydrolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mycobacterium erythropolis gray and thornton 1928]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Limonene-1,2-epoxide hydrolase]]
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[[Category: Rhodococcus erythropolis]]
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[[Category: Kong, X D]]
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[[Category: Kong XD]]
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[[Category: Lonsdale, R]]
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[[Category: Lonsdale R]]
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[[Category: Reetz, M T]]
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[[Category: Reetz MT]]
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[[Category: Sun, Z]]
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[[Category: Sun Z]]
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[[Category: Xu, J H]]
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[[Category: Xu JH]]
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[[Category: Zhou, J]]
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[[Category: Zhou J]]
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[[Category: Epoxide hydrolase]]
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[[Category: Hydrolase]]
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Revision as of 21:24, 12 April 2023

Crystal Structure of the L74F/M78V/I80V/L114F mutant of LEH complexed with cyclohexanediol

PDB ID 4xdv

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