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4y10

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<StructureSection load='4y10' size='340' side='right'caption='[[4y10]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
<StructureSection load='4y10' size='340' side='right'caption='[[4y10]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4y10]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y10 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y10 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4y10]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y10 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=OBF:(2S)-2-AMINO-4,4-DIFLUOROBUTANOIC+ACID'>OBF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OBF:(2S)-2-AMINO-4,4-DIFLUOROBUTANOIC+ACID'>OBF</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y10 OCA], [https://pdbe.org/4y10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y10 RCSB], [https://www.ebi.ac.uk/pdbsum/4y10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y10 ProSAT]</span></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y0y|4y0y]], [[4y0z|4y0z]], [[4y11|4y11]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y10 OCA], [http://pdbe.org/4y10 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y10 RCSB], [http://www.ebi.ac.uk/pdbsum/4y10 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y10 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BPT1_BOVIN BPT1_BOVIN]] Inhibits trypsin, kallikrein, chymotrypsin, and plasmin.
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[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[BPTI 3D structures|BPTI 3D structures]]
*[[BPTI 3D structures|BPTI 3D structures]]
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*[[Trypsin|Trypsin]]
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*[[Trypsin 3D structures|Trypsin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Trypsin]]
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[[Category: Alings C]]
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[[Category: Alings, C]]
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[[Category: Berger AA]]
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[[Category: Berger, A A]]
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[[Category: Koksch B]]
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[[Category: Koksch, B]]
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[[Category: Loll B]]
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[[Category: Loll, B]]
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[[Category: Muelow U]]
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[[Category: Muelow, U]]
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[[Category: Wahl MC]]
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[[Category: Wahl, M C]]
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[[Category: Ye S]]
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[[Category: Ye, S]]
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[[Category: Digestion]]
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[[Category: Hydrolase inhibitor]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Metal-binding]]
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[[Category: Protease]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Zymogen]]
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Revision as of 18:02, 26 April 2023

Trypsin in complex with with BPTI mutant (2S)-2-amino-4,4-difluorobutanoic acid

PDB ID 4y10

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