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Gp120 3D structures
From Proteopedia
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *Gp120 from HIV-1; Domains – Clade A/E 1-140; outer – 1-181; RHPA 1-216; V1-V2 118-246; V3 296-331; core | + | *Gp120 from HIV-1; Domains – Clade A/E 1-140; outer – 1-181; RHPA 1-216; V1-V2 118-246; V3 296-331; core 1-353; C5 484-506 |
| - | **[[3dnl]], [[3dnn]], [[3dno]], [[3tgq]], [[3tgr]], [[3tgt]], [[3tih]], [[5f4u]] - Gp120 core<br /> | + | **[[3dnl]], [[3dnn]], [[3dno]], [[3tgq]], [[3tgr]], [[3tgt]], [[3tih]], [[5f4u]], [[6utb]], [[6utd]] - Gp120 core<br /> |
**[[5fa2]] - Gp120 core (mutant)<br /> | **[[5fa2]] - Gp120 core (mutant)<br /> | ||
**[[1meq]] – GP120 C5 domain – NMR<br /> | **[[1meq]] – GP120 C5 domain – NMR<br /> | ||
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**[[4jpj]], [[5idl]] - Gp120 outer domain<br /> | **[[4jpj]], [[5idl]] - Gp120 outer domain<br /> | ||
| - | *Gp120 binary complex | + | *Gp120+antibody binary complex |
| - | **[[4jb9]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lsu]], [[5te6]], [[5fcu]], [[5f9w]], [[5f9o]], [[5f96]], [[5cd5]], [[4xvt]] - Gp120 Clade A/E + antibody <br /> | + | **[[4jb9]], [[4jpj]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lsu]], [[4olu]], [[4olv]], [[4olx]], [[4olz]], [[4om0]], [[4om1]], [[4rx4]], [[4xmp]], [[4ydi]], [[4ydj]], [[4ydk]], [[5i9q]], [[5te6]], [[5fcu]], [[5f9w]], [[5f9o]], [[5f96]], [[5cd5]], [[4xvt]], [[6oej]], [[6p8m]], [[6xcj]], [[7jks]], [[7jkt]], [[7klc]], [[7kmd]], [[7n8q]] - Gp120 Clade A/E + antibody <br /> |
| - | **[[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]] - Gp120 Clade A/E (mutant) + antibody <br /> | + | **[[4xnz]], [[6n1w]], [[7mep]], [[7t74]], [[7t76]] - Gp120 Clade A/E + antibody – Cryo EM<br /> |
| - | **[[4i3r]], [[4i3s]], [[5kzc]], [[5if0]], [[5ies]], [[4jpv]] - Gp120 outer domain + antibody<br /> | + | **[[3u7y]], [[4jpw]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[6ofi]] - Gp120 Clade A/E (mutant) + antibody <br /> |
| + | **[[4olw]], [[4oly]], [[7sx6]], [[7sx7]] - Gp120 core + antibody<br /> | ||
| + | **[[3tyg]], [[4i3r]], [[4i3s]], [[5kzc]], [[5if0]], [[5ies]], [[4jpv]] - Gp120 outer domain + antibody<br /> | ||
**[[5t33]] - Gp120 RHPA + antibody <br /> | **[[5t33]] - Gp120 RHPA + antibody <br /> | ||
**[[3u2s]] - Gp120 V1V2 region + antibody PG9<br /> | **[[3u2s]] - Gp120 V1V2 region + antibody PG9<br /> | ||
| - | **[[3se8]], [[3se9]], [[3hi1]], [[3rjq]], [[4jkp]], [[4jm2]], [[4lss]], [[4lsv]], [[4ywg]], [[4xvs]], [[3ngb]], [[4ye4]], [[4rwy]], [[4jan]], [[4lst]], [[5te7]], [[5f6j]], [[5te4]], [[6bf4]], [[5wb9]], [[5w6d]], [[5ukr]], [[5uem]], [[5igx]], [[4dvr]] - Gp120 + antibody<br /> | + | **[[3se8]], [[3se9]], [[3hi1]], [[3rjq]], [[4jkp]], [[4jm2]], [[4lss]], [[4lsv]], [[4ywg]], [[4xvs]], [[3ngb]], [[4ye4]], [[4rwy]], [[4jan]], [[4lst]], [[5te7]], [[5f6j]], [[5te4]], [[6bf4]], [[5wb9]], [[5w6d]], [[5ukr]], [[5uem]], [[5igx]], [[4dvr]] - Gp120 core + antibody<br /> |
| - | **[[3idx]], [[3idy]], [[2ny7]]. [[4jdt]], [[5fyl]], [[5fec]], [[6bck]] - Gp120 core (mutant) + antibody <br /> | + | **[[3idx]], [[3idy]], [[2ny7]]. [[4jdt]], [[5fyl]], [[5fec]], [[6bck]], [[6oz2]], [[6oz3]] - Gp120 core (mutant) + antibody <br /> |
| + | **[[3mls]], [[3mlw]], [[4jo3]], [[6db5]], [[6db7]] - Gp120 V3 + antibody <br /> | ||
| + | **[[1qnz]] - Gp120 V3 + antibody - NMR<br /> | ||
| + | **[[6cez]], [[6vbo]], [[6vbp]], [[6vbq]] - Gp120 V2 + antibody <br /> | ||
| + | **[[7r73]], [[7r74]], [[7ri1]], [[7ri2]] - Gp120 core + VHH <br /> | ||
| + | |||
| + | *Gp120 other binary complex | ||
| + | |||
| + | **[[6v0r]], [[6vfl]], [[6vrw]], [[7l7t]], [[7l7u]] [[6vfl]], [[7sc5]], [[7ska]] - Gp120 Clade A/E + Gp41 core – Cryo EM<br /> | ||
| + | **[[7l6o]] - Gp120 Clade A/E (mutant) + Gp41 core <br /> | ||
| + | **[[6vl5]] - Gp120 Clade A/E + Gp41 core – synthetic - Cryo EM<br /> | ||
| + | **[[4i54]], [[7rsx]], [[7rsy]], [[7rsz]], [[7tjo]], [[7tjp]], [[8dcq]], [[8fly]], [[8flz]], [[8fm0]], [[8fm2]], [[8fm3]], [[8fm4]], [[8fm5]], [[8fm7]], [[8fm8]] - Gp120 Clade A/E + inhibitor <br /> | ||
| + | **[[4i53]], [[7rdw]], [[8f9z]] - Gp120 core + inhibitor <br /> | ||
| + | **[[6usw]], [[8fa0]] - Gp120 core (mutant) + inhibitor <br /> | ||
| + | **[[6l1y]] - Gp120 core + CD4 <br /> | ||
**[[4rz8]], [[5f4l]], [[5f4p]], [[5f4r]] - Gp120 core + CD4 mimic <br /> | **[[4rz8]], [[5f4l]], [[5f4p]], [[5f4r]] - Gp120 core + CD4 mimic <br /> | ||
**[[4dku]], [[4dkv]] - Gp120 core (mutant) + CD4 mimetic<br /> | **[[4dku]], [[4dkv]] - Gp120 core (mutant) + CD4 mimetic<br /> | ||
**[[4jzw]], [[4jzz]], [[4k0a]], [[4ka2]] - Gp120 core + CD4 mimetic miniprotein<br /> | **[[4jzw]], [[4jzz]], [[4k0a]], [[4ka2]] - Gp120 core + CD4 mimetic miniprotein<br /> | ||
| - | **[[ | + | **[[6one]], [[6onf]], [[6onh]], [[6onv]], [[6p9n]] - Gp120 Clade A/E (mutant) + CD4 mimetic<br /> |
| - | **[[3tgs]], [[4dko]], [[4dkp]], [[4dkq]], [[4dkr]] - Gp120 core + piperidine derivative<br /> | + | **[[3tgs]], [[4dko]], [[4dkp]], [[4dkq]], [[4dkr]], [[6ooo]] - Gp120 core + piperidine derivative<br /> |
**[[5u6e]] - Gp120 core + pyrrole derivative<br /> | **[[5u6e]] - Gp120 core + pyrrole derivative<br /> | ||
| - | **[[4dvx]], [[4dvw]], [[4dvv]], [[4dvt]], [[4dvs]] - Gp120 core (mutant) + piperazine derivative<br /> | + | **[[4dvx]], [[4dvw]], [[4dvv]], [[4dvt]], [[4dvs]], [[6usw]] - Gp120 core (mutant) + piperazine derivative<br /> |
| + | **[[6ut1]] - Gp120 core (mutant) + inhibitor<br /> | ||
| - | *Gp120 | + | *Gp120 higher complex |
| - | **[[5kjr]] - Gp120 Clade A/E + M48U1 peptide + antibody<br /> | + | **[[5kjr]], [[6mfp]] - Gp120 Clade A/E + M48U1 peptide + antibody<br /> |
| - | **[[4rfo]], [[4rfn]] - Gp120 Clade A/E (mutant) + M48U1 peptide + antibody<br /> | + | **[[4rfo]], [[4rfn]], [[6mg7]] - Gp120 Clade A/E 4-492 (mutant) + M48U1 peptide + antibody<br /> |
| - | **[[4h8w]] - Gp120 Clade A/E + CD4 + antibody<br /> | + | **[[2qad]], [[3lqa]], [[4h8w]] - Gp120 Clade A/E + CD4 + antibody<br /> |
| + | **[[4tvp]], [[6utk]], [[6vkn]], [[6v6w]], [[7kmd]], [[7ucf]] - Gp120 Clade A/E + Gp41 core + antibody <br /> | ||
| + | **[[3j5m]], [[6mpg]], [[6mph]], [[6n1v]], [[6n1w]], [[6nf2]], [[6nfc]], [[6x96]], [[6x97]], [[7kde]], [[7lg6]], [[7lu9]], [[7lxm]], [[7lxn]], [[7ly9]], [[7mdt]], [[7mdu]], [[7mxe]], [[7pc2]], [[7rsn]], [[7rso]], [[7sd3]], [[7sq1]], [[7t73]], [[7t74]], [[7t75]], [[7t76]], [[7t77]], [[7tfn]], [[7tfo]], [[7ugn]], [[7ugp]], [[7ugq]], [[7z3a]], [[7zlk]], [[8fis]] - Gp120 Clade A/E + Gp41 core + antibody – Cryo EM<br /> | ||
| + | **[[6x98]], [[6ot1]], [[7n28]] - Gp120 Clade A/E (mutant) + Gp41 core + antibody – Cryo EM<br /> | ||
| + | **[[7lpn]] - Gp120 Clade A/E + Gp41 core + VHH – Cryo EM<br /> | ||
**[[3jwd]], [[3jwo]], [[2i5y]], [[2i60]] - Gp120 core + hCD4 N terminal + antibody <br /> | **[[3jwd]], [[3jwo]], [[2i5y]], [[2i60]] - Gp120 core + hCD4 N terminal + antibody <br /> | ||
**[[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[1gc1]], [[1g9m]], [[1g9n]], [[1rzj]], [[1rzk]], [[1yyl]], [[1yym]], [[2b4c]] - Gp120 core (mutant) + hCD4 N terminal + antibody <br /> | **[[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[1gc1]], [[1g9m]], [[1g9n]], [[1rzj]], [[1rzk]], [[1yyl]], [[1yym]], [[2b4c]] - Gp120 core (mutant) + hCD4 N terminal + antibody <br /> | ||
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**[[5w4l]], [[6w4m]] - Gp120 core (mutant) + CD4 mimetic peptide + antibody<br /> | **[[5w4l]], [[6w4m]] - Gp120 core (mutant) + CD4 mimetic peptide + antibody<br /> | ||
**[[4r4f]], [[4r4n]] - Gp120 core + M48U1 peptide + antibody<br /> | **[[4r4f]], [[4r4n]] - Gp120 core + M48U1 peptide + antibody<br /> | ||
| - | **[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k | + | **[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]], [[6mft]], [[6mdt]], [[6mco]], [[6d2p]], [[6ck9]], [[6ch9]], [[6ch8]], [[6ch7]], [[6wix]] - Gp120 core + Gp41 + antibody<br /> |
| + | **[[6ccb]], [[6x5b]], [[6x9r]], [[6x9s]], [[6x9t]], [[6x9u]], [[6x9v]], [[6xrt]], [[7n65]], [[7pc2]], [[7rai]] - Gp120 29-504 (mutant) + Gp41 + antibody<br /> | ||
| + | **[[6cde]], [[6cdi]], [[6okp]], [[6e5p]], [[6cuf]], [[6cue]], [[6chb]], [[5u1f]], [[5thr]], [[4cc8]], [[3j70]], [[6udj]], [[6udk]], [[6v8z]], [[6vlr]], [[6vo1]], [[6vtt]], [[7lo6]], [[7mxd]], [[7ugo]] - Gp120 core + Gp41 + antibody – Cryo EM<br /> | ||
| + | **[[6mn7]], [[6nqd]], [[6olp]], [[6orn]], [[6oro]], [[6orp]], [[6orq]], [[6osy]], [[6pw6]], [[6u59]], [[6uda]], [[6ulc]], [[6um6]], [[6um7]], [[6v8x]], [[6vi0]], [[6vo0]], [[6vo3]], [[6vtt]], [[6vy2]], [[7l86]], [[7l87]], [[7l88]], [[7l89]], [[7l8a]], [[7l8b]], [[7l8c]], [[7l8d]], [[7l8s]], [[7l8t]], [[7l8u]], [[7l8w]], [[7l8x]], [[7l8y]], [[7l8z]], [[7l90]], [[7ll1]], [[7ll2]], [[7llk]], [[7lua]] - Gp120 29-508 + Gp41 + antibody – Cryo EM<br /> | ||
| + | **[[6nc2]], [[6nc3]] - Gp120 29-508 (mutant) + Gp41 + antibody – Cryo EM<br /> | ||
**[[5fyk]], [[5fyj]], [[4nco]], [[6nnj]], [[6nnf]], [[6nm6]] - Gp120 core (mutant) + Gp41 + antibody<br /> | **[[5fyk]], [[5fyj]], [[4nco]], [[6nnj]], [[6nnf]], [[6nm6]] - Gp120 core (mutant) + Gp41 + antibody<br /> | ||
| - | **[[6cde]], [[6cdi]], [[6orn]], [[6oro]], [[6orp]], [[6orq]], [[6okp]], [[6nqd]], [[6nc3]], [[6nc2]], [[6mn7]], [[6e5p]], [[6cuf]], [[6cue]], [[6chb]], [[5u1f]], [[5thr]], [[4cc8]], [[3j70]] - Gp120 core + Gp41 + antibody – Cryo EM<br /> | ||
**[[3j5m]] - Gp120 core (mutant) + Gp41 + antibody – Cryo EM<br /> | **[[3j5m]] - Gp120 core (mutant) + Gp41 + antibody – Cryo EM<br /> | ||
| + | **[[6u0l]], [[6u0n]], [[8d5c]] - Gp120 32-505 + Gp41 + antibody + CD4 – Cryo EM<br /> | ||
| + | **[[6um5]] - Gp120 30-489 + Gp41 + antibody + CH848 – Cryo EM<br /> | ||
| + | **[[6vpx]], [[7lok]] - Gp120 core + Gp41 + antibody + peptide – Cryo EM<br /> | ||
| + | **[[7txd]] – Gp120 core + Gp41 + darpin + CD4 – Cryo EM<br /> | ||
*Gp120 from HIV-2 binary complex | *Gp120 from HIV-2 binary complex | ||
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**[[2bf1]], [[3fus]] - Gp120 core<br /> | **[[2bf1]], [[3fus]] - Gp120 core<br /> | ||
**[[3jcc]], [[3jcb]] - Gp120 core + CD4 + antibody – Cryo EM<br /> | **[[3jcc]], [[3jcb]] - Gp120 core + CD4 + antibody – Cryo EM<br /> | ||
| + | **[[7t2p]], [[7t4g]], [[8dua]] - Gp120 + Gp41 core + antibody – Cryo EM<br /> | ||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
3D structures of Gp120
Updated on 27-April-2023
