Heat Shock Protein structures

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Line 29: Line 29:
**[[4ylb]], [[4ylc]] - SsHsp20 (mutant)<br />
**[[4ylb]], [[4ylc]] - SsHsp20 (mutant)<br />
**[[5z81]] – VcHsp15 – ''Vibrio cholerae''<br />
**[[5z81]] – VcHsp15 – ''Vibrio cholerae''<br />
 +
**[[4i2n]] – VcHsp31<br />
**[[3bbu]] – EcHsp15 - ''Escherichia coli'' – Cryo-EM<br />
**[[3bbu]] – EcHsp15 - ''Escherichia coli'' – Cryo-EM<br />
 +
**[[1dm9]] – EcHsp15<br />
 +
**[[8ap4]] – EcHsp15 in 50S ribosome – Cryo-EM<br />
**[[1ons]] – EcHsp31<br />
**[[1ons]] – EcHsp31<br />
**[[3gla]], [[3gt6]], [[3guf]] – Hsp – ''Xanthomonas axonopodis''<br />
**[[3gla]], [[3gt6]], [[3guf]] – Hsp – ''Xanthomonas axonopodis''<br />
-
**[[3vqk]] – StHsp14 – ''Sulfolobus tokodaii''<br />
+
**[[3aac]], [3vqk]] – StHsp14 – ''Sulfolobus tokodaii''<br />
-
**[[3vql]], [[3vqm]] – StHsp14 (mutant)<br />
+
**[[3aab]], [[3vql]], [[3vqm]] – StHsp14 (mutant)<br />
**[[3w1z]] – Hsp16 – ''Schizosacchromyces pombe''<br />
**[[3w1z]] – Hsp16 – ''Schizosacchromyces pombe''<br />
**[[5j7n]] – Hsp – ''Xylella fastidiosa''<br />
**[[5j7n]] – Hsp – ''Xylella fastidiosa''<br />
 +
**[[6l6m]] – Hsp18.5 – ''Entamoeba histolytica''<br />
 +
**[[4fei]] – Hsp17.7 – ''Deinococcus radiodurans''<br />
**[[1shs]], [[4eld]], [[4i88]] – Hsp – ''Methanococcus jannaschii''<br />
**[[1shs]], [[4eld]], [[4i88]] – Hsp – ''Methanococcus jannaschii''<br />
**[[2bol]] – Hsp – ''Taenia saginata''<br />
**[[2bol]] – Hsp – ''Taenia saginata''<br />
Line 45: Line 50:
*Hsp33
*Hsp33
 +
**[[3kkl]] – yHsp33 <br />
**[[1hw7]], [[3m7m]] – EcHsp33 NTD <br />
**[[1hw7]], [[3m7m]] – EcHsp33 NTD <br />
**[[1i7f]] – EcHsp33 chaperone domain (mutant)<br />
**[[1i7f]] – EcHsp33 chaperone domain (mutant)<br />
Line 69: Line 75:
**[[2qld]] – hHsp40 residues 158-340<br />
**[[2qld]] – hHsp40 residues 158-340<br />
-
**[[1hdj]], [[2ctq]], [[6iws]] – hHsp40 J domain 1-76 - NMR<br />
+
**[[1hdj]], [[2ctq]], [[2lgw]], [[2m6y]], [[6iws]] – hHsp40 J domain 1-76 - NMR<br />
 +
**[[6byr]] – hHsp40 J domain 1-70 + CAMP-dependent protein kinase<br />
**[[6z5n]] – hHsp40 1-110 – NMR<br />
**[[6z5n]] – hHsp40 1-110 – NMR<br />
**[[6cgh]] – hHsp40 346-432 – NMR<br />
**[[6cgh]] – hHsp40 346-432 – NMR<br />
**[[6u3r]], [[6u3s]] – hHsp40 1-127+CT – NMR<br />
**[[6u3r]], [[6u3s]] – hHsp40 1-127+CT – NMR<br />
**[[7jsq]] – hHsp40 CT – NMR<br />
**[[7jsq]] – hHsp40 CT – NMR<br />
 +
**[[7ndx]] – hHsp40 CT + NudC peptide<br />
**[[7ciz]], [[7cj0]] – hHsp40 CT + DNA replication licensing factor + histone H3.4 + histone H4<br />
**[[7ciz]], [[7cj0]] – hHsp40 CT + DNA replication licensing factor + histone H3.4 + histone H4<br />
**[[6jmg]] – DnaJ + GTP - frog<br />
**[[6jmg]] – DnaJ + GTP - frog<br />
Line 90: Line 98:
*Hsp47
*Hsp47
-
**[[3zha]] – dHsp47 + collagen peptide - dog<br />
+
**[[4au4]] – dHsp47 - dog<br />
 +
**[[3zha]] – dHsp47 + collagen peptide<br />
* Hsp60 mitochondrial
* Hsp60 mitochondrial
-
**[[7azp]] – hHsp60 – Cryo EM<br />
+
**[[7azp]], [[7l7l]], [[7l7s]] – hHsp60 – Cryo EM<br />
-
**[[4pj1]], [[6ht7]] – hHsp60 + hHsp10<br />
+
**[[4pj1]], [[6ht7]] – hHsp60 + hHsp10 + ADP<br />
**[[6mrc]], [[6mrd]] – hHsp60 + hHsp10 + ADP – Cryo EM<br />
**[[6mrc]], [[6mrd]] – hHsp60 + hHsp10 + ADP – Cryo EM<br />
Line 103: Line 112:
**[[3iyf]] - MmHsp60 - GroEL – open state<br />
**[[3iyf]] - MmHsp60 - GroEL – open state<br />
**[[3e76]] – EcHsp60 – GroEL+Tl ion – ''Escherichia coli''<br />
**[[3e76]] – EcHsp60 – GroEL+Tl ion – ''Escherichia coli''<br />
-
**[[2nwc]], [[1oel]], [[1grl]], [[1la1]] - EcHsp60 – GroEL<br />
+
**[[2nwc]], [[1oel]], [[1grl]], [[1la1]], [[7v98]] - EcHsp60 – GroEL<br />
-
**[[2eu1]] - EcHsp60 (mutant) – GroEL<br />
+
**[[2eu1]], [[7v9r]] - EcHsp60 (mutant) – GroEL<br />
**[[2cgt]] - EcHsp60 – GroEL+ADP+capsid assembly protein Gp31<br />
**[[2cgt]] - EcHsp60 – GroEL+ADP+capsid assembly protein Gp31<br />
**[[2c7c]], [[2c7d]] - EcHsp60 – GroEL+GroES – cryo EM<br />
**[[2c7c]], [[2c7d]] - EcHsp60 – GroEL+GroES – cryo EM<br />
Line 115: Line 124:
**[[4v4o]] - TtHsp60 – GroEL+GroES <br />
**[[4v4o]] - TtHsp60 – GroEL+GroES <br />
**[[1ass]], [[1asx]] - Hsp60 – GroEL apical domain – ''Thermoplasma acidophilum''<br />
**[[1ass]], [[1asx]] - Hsp60 – GroEL apical domain – ''Thermoplasma acidophilum''<br />
 +
 +
* Hsp65
 +
 +
**[[3rtk]] – MtHsp65 – ''Mycobacterium tuberculosis''<br />
* Hsp70 – 3 domains: N-terminus ATPase hydrolyzes ATP to ADP (NBD) residues 1-380; hydrophobic amino acid binding domain (SBD) residues 381-564: C-terminus lid domain (CT) residues 534-641.
* Hsp70 – 3 domains: N-terminus ATPase hydrolyzes ATP to ADP (NBD) residues 1-380; hydrophobic amino acid binding domain (SBD) residues 381-564: C-terminus lid domain (CT) residues 534-641.
Line 150: Line 163:
**[[6s02]] – PfHsp70 NTD+ADP <br />
**[[6s02]] – PfHsp70 NTD+ADP <br />
**[[7ooe]], [[7oog]], [[7ooh]], [[7p31]] – PfHsp70 NTD+AMP derivative + inhibitor <br />
**[[7ooe]], [[7oog]], [[7ooh]], [[7p31]] – PfHsp70 NTD+AMP derivative + inhibitor <br />
 +
**[[7nqr]], [[7nqs]], [[7nqu]], [[7nqz]] - PfHsp70 NBD + inhibitor<br />
**[[6zhi]] - PfHsp70 CT + peptide<br />
**[[6zhi]] - PfHsp70 CT + peptide<br />
Line 161: Line 175:
**[[4b9q]] - EcDnaK NBD + SBD + ATP<br />
**[[4b9q]] - EcDnaK NBD + SBD + ATP<br />
 +
**[[7ko2]], [[7krt]], [[7kru]], [[7krv]] - EcDnaK (mutant) + ATP<br />
**[[5oow]] - EcDnaK + AMPPCP<br />
**[[5oow]] - EcDnaK + AMPPCP<br />
**[[5nro]] – EcDnaK (mutant) + DnaJ<br />
**[[5nro]] – EcDnaK (mutant) + DnaJ<br />
Line 172: Line 187:
**[[1q5l]] - EcDnaK SBD + peptide – NMR<br />
**[[1q5l]] - EcDnaK SBD + peptide – NMR<br />
**[[3dpp]], [[3dpq]], [[3dpo]], [[1dky]], [[3qnj]], [[4e81]], [[4ezn]], [[4ezo]], [[4ezp]], [[4ezq]], [[4ezr]], [[4ezs]], [[4ezt]], [[4ezu]], [[4ezv]], [[4ezw]], [[4ezx]], [[4ezy]], [[4ezz]], [[4f00]], [[4hy9]], [[4hyb]], [[4jwc]], [[4jwd]], [[4jwe]], [[4jwi]], [[4r5i]], [[4f01]], [[7jmm]], [[7jn8]], [[7jn9]], [[7jne]], [[7n6j]], [[7n6k]], [[7n6l]], [[7n6m]] – EcDnaK SBD + peptide<br />
**[[3dpp]], [[3dpq]], [[3dpo]], [[1dky]], [[3qnj]], [[4e81]], [[4ezn]], [[4ezo]], [[4ezp]], [[4ezq]], [[4ezr]], [[4ezs]], [[4ezt]], [[4ezu]], [[4ezv]], [[4ezw]], [[4ezx]], [[4ezy]], [[4ezz]], [[4f00]], [[4hy9]], [[4hyb]], [[4jwc]], [[4jwd]], [[4jwe]], [[4jwi]], [[4r5i]], [[4f01]], [[7jmm]], [[7jn8]], [[7jn9]], [[7jne]], [[7n6j]], [[7n6k]], [[7n6l]], [[7n6m]] – EcDnaK SBD + peptide<br />
-
**[[7kzi]], [[7kzu]] – EcDnaK/peptide<br />
+
**[[7krw]], [[7kzi]], [[7kzu]] – EcDnaK/peptide<br />
**[[1q5l]] - EcDnaK SBD +peptide – NMR<br />
**[[1q5l]] - EcDnaK SBD +peptide – NMR<br />
**[[4r5g]] - EcDnaK CT + inhibitor<br />
**[[4r5g]] - EcDnaK CT + inhibitor<br />
Line 186: Line 201:
**[[5f3k]], [[5f5r]] – hHsp75 NTD<br />
**[[5f3k]], [[5f5r]] – hHsp75 NTD<br />
-
**[[5hph]] – hHsp75 residues 60-554<br />
+
**[[5hph]], [[7ulk]] – hHsp75 residues 60-554<br />
**[[4z1f]], [[4z1g]], [[4z1h]], [[4z1i]], [[5y3n]], [[5y3o]], [[7c04]], [[7c05]], [[7c7b]], [[7c7c]] – hHsp75 + inhibitor<br />
**[[4z1f]], [[4z1g]], [[4z1h]], [[4z1i]], [[5y3n]], [[5y3o]], [[7c04]], [[7c05]], [[7c7b]], [[7c7c]] – hHsp75 + inhibitor<br />
 +
**[[6xg6]] – hHsp75 residues 60-704 + ADP – Cryo EM<br />
 +
**[[7kck]], [[7klu]], [[7klv]] – hHsp75 residues 60-704 + AMPPNP – Cryo EM<br />
 +
**[[7kcl]], [[7kcm]] – hHsp75 residues 60-704 + SDHB + AMPPNP – Cryo EM<br />
*Hsp83
*Hsp83
Line 193: Line 211:
**[[3u67]] – LmHsp83 NTD + ADP – ''Leishmania major''
**[[3u67]] – LmHsp83 NTD + ADP – ''Leishmania major''
-
* Hsp90 – 4 domains: N-terminus (NTD) residues 1-236; linker; middle (MD); C-terminus (CT)
+
* Hsp90 – 4 domains: N-terminus (NTD) residues 1-236; linker 237-283; middle (MD) 284-543; C-terminus (CT)
*''Hsp90-α NTD''
*''Hsp90-α NTD''
-
**[[3t0h]], [[5j2v]], [[6gpw]] - hHsp90 NTD – human<br />
+
**[[3t0h]], [[5j2v]], [[6gpw]], [[7s8y]], [[7s8z]][[5xr]], - hHsp90 NTD – human<br />
**[[5j80]], [[6gr4]], [[6gp4]] - hHsp90 NTD (mutant)<br />
**[[5j80]], [[6gr4]], [[6gp4]] - hHsp90 NTD (mutant)<br />
**[[2h8m]], [[2hch]], [[2gqp]] – dHsp90B1 NTD <br />
**[[2h8m]], [[2hch]], [[2gqp]] – dHsp90B1 NTD <br />
Line 216: Line 234:
**[[2k5b]] - hHsp90 NTD+Cdc37 – NMR - docking<br />
**[[2k5b]] - hHsp90 NTD+Cdc37 – NMR - docking<br />
**[[3eko]], [[3ekr]] - hHsp90 NTD+dihydroxyphenyl amide<br />
**[[3eko]], [[3ekr]] - hHsp90 NTD+dihydroxyphenyl amide<br />
-
**[[3bm9]], [[3bmy]], [[5xre]], [[5xrb]], [[5xr9]], [[5xr5]], [[5xqe]], [[5xqd]] - hHsp90 NTD+ oxazole derivative<br />
+
**[[3bm9]], [[3bmy]], [[5xrd]], [[5xre]], [[5xrb]], [[5xr9]], [[5xr5]], [[5xqe]], [[5xqd]] - hHsp90 NTD+ oxazole derivative<br />
**[[2of6]], [[3b24]], [[3b27]], [[3b28]], [[3r92]] - hHsp90 NTD+triazine derivative<br />
**[[2of6]], [[3b24]], [[3b27]], [[3b28]], [[3r92]] - hHsp90 NTD+triazine derivative<br />
-
**[[5j20]], [[5j27]], [[5j2x]], [[5j64]], [[5j6l]], [[5j6m]], [[5j82]], [[5j86]], [[5j8m]], [[5j6n]], [[5j8u]], [[5j9x]] - hHsp90-α NTD - hHsp90-a NTD+triazol derivative<br />
+
**[[5j20]], [[5j27]], [[5j2x]], [[5j64]], [[5j6l]], [[5j6m]], [[5j82]], [[5j86]], [[5j8m]], [[5j6n]], [[5j8u]], [[5j9x]], [[8agi]], [[8agl]] - hHsp90-α NTD +triazol derivative<br />
-
**[[2qfo]], [[3nmq]], [[3r4m]], [[3r4n]], [[3r4o]], [[3r4p]], [[3b25]], [[3b26]], [[2jcc]], [[3rlp]], [[3rlq]], [[3rlr]], [[2wi1]], [[2wi2]], [[2wi3]], [[2wi4]], [[2wi5]], [[2wi6]], [[2wi7]], [[2jjc]], [[5fnc]] - hHsp90 NTD+pyrimidine derivative<br />
+
**[[8agj]] - hHsp90-a NTD (mutant) +triazol derivative<br />
 +
**[[2qfo]], [[3nmq]], [[3r4m]], [[3r4n]], [[3r4o]], [[3r4p]], [[3b25]], [[3b26]], [[2jcc]], [[3rlp]], [[3rlq]], [[3rlr]], [[2wi1]], [[2wi2]], [[2wi3]], [[2wi4]], [[2wi5]], [[2wi6]], [[2wi7]], [[2jjc]], [[5fnc]], [[7dmc]], [[7s98]], [[7s99]], [[7s9f]], [[7s9g]], [[7s9h]], [[7s9i]] - hHsp90 NTD+pyrimidine derivative<br />
 +
**[[7a90]], [[7s95]] - hHsp90 NTD+ adenine <br />
**[[6f1n]] - hHsp90 NTD+pyridine derivative<br />
**[[6f1n]] - hHsp90 NTD+pyridine derivative<br />
**[[1uy6]], [[1uy7]], [[1uy8]], [[1uy9]], [[1uyc]], [[1uyd]], [[1uye]], [[1uyf]], [[1uyg]], [[1uyh]], [[1uyi]], [[1uyk]], [[1uyl]], [[6el5]], [[2fwy]], [[2fwz]], [[2h55]], [[3o0i]], [[6cyh]], [[6cyg]], [[6b9a]], [[6b99]] - hHsp90 NTD+purine derivative<br />
**[[1uy6]], [[1uy7]], [[1uy8]], [[1uy9]], [[1uyc]], [[1uyd]], [[1uye]], [[1uyf]], [[1uyg]], [[1uyh]], [[1uyi]], [[1uyk]], [[1uyl]], [[6el5]], [[2fwy]], [[2fwz]], [[2h55]], [[3o0i]], [[6cyh]], [[6cyg]], [[6b9a]], [[6b99]] - hHsp90 NTD+purine derivative<br />
Line 253: Line 273:
**[[6cjr]], [[6cjs]] – CaHsp90 NTD + inhibitor<br />
**[[6cjr]], [[6cjs]] – CaHsp90 NTD + inhibitor<br />
**[[7k9s]], [[7k9u]], [[7k9v]], [[7k9w]] – CnHsp90 NTD + inhibitor<br />
**[[7k9s]], [[7k9u]], [[7k9v]], [[7k9w]] – CnHsp90 NTD + inhibitor<br />
 +
 +
''Hsp90-a NTD+linker residues 1-293''
 +
 +
**[[7ur3]] - hHsp90 + inhibitor <br />
*''Hsp90-α MD''
*''Hsp90-α MD''
 +
**[[6ksq]] - hHsp90 MD <br />
**[[2gq0]] - EcHsp90 MD<br />
**[[2gq0]] - EcHsp90 MD<br />
Line 269: Line 294:
*''Hsp90-α MD + CT'' residues 293-732
*''Hsp90-α MD + CT'' residues 293-732
-
**[[3q6m]], [[3q6n]] - hHsp90 MD + CT<br />
+
**[[3q6m]], [[3q6n]], [[7rxz]], [[7ry0]], [[7ry1]] - hHsp90 MD + CT<br />
**[[2o1t]] – dHsp90B1 MD+CT<br />
**[[2o1t]] – dHsp90B1 MD+CT<br />
-
*''Hsp90-α full length''
+
*''Hsp90-α full length 1-732''
-
**[[6xg6]] - hHsp90 + ADP – Cryo EM <br />
 
**[[2qf6]] - hHsp90 + antigen<br />
**[[2qf6]] - hHsp90 + antigen<br />
**[[5fwk]], [[5fwl]], [[5fwm]], [[5fwp]] – hHsp90 + CDC37 + CDK4<br />
**[[5fwk]], [[5fwl]], [[5fwm]], [[5fwp]] – hHsp90 + CDC37 + CDK4<br />
 +
**[[7l7j]] - hHsp90 + P23 + ANP – Cryo EM <br />
 +
**[[7krj]] - hHsp90 + GR + P23 + ATP – Cryo EM <br />
 +
**[[8h77]] - hHsp90 + AhR + P23 + XAP2 + ADP – Cryo EM <br />
 +
**[[7l7i]] - hHsp90 + FKBP51 + P23 + ANP – Cryo EM <br />
 +
**[[7kw7]] - hHsp90 + Hsp70 + GR + STI1 + ADP – Cryo EM <br />
**[[2o1u]] – dHsp90B1+AMPPNP<br />
**[[2o1u]] – dHsp90B1+AMPPNP<br />
**[[2o1v]] - dHsp90B1+ADP<br />
**[[2o1v]] - dHsp90B1+ADP<br />
Line 284: Line 313:
*Hsp90-β
*Hsp90-β
 +
**[[8eob]] - hHsp90 – Cryo EM <br />
**[[6n8w]] - hHsp90 NTD <br />
**[[6n8w]] - hHsp90 NTD <br />
**[[5fwk]], [[5fwl]], [[5fwm]], [[5fwp]] – hHsp90 + CDC37 + CDK4<br />
**[[5fwk]], [[5fwl]], [[5fwm]], [[5fwp]] – hHsp90 + CDC37 + CDK4<br />
-
**[[1uym]], [[6n8y]] - hHsp90 NTD+ purine inhibitor<br />
+
**[[1uym]], [[6n8y]], [[7ulj]] - hHsp90 NTD+ purine inhibitor<br />
**[[5uc4]], [[5uch]], [[5uci]], [[5ucj]], [[4o04]], [[4o05]], **[[4o07]] - hHsp90-b NTD + inhibitor<br />
**[[5uc4]], [[5uch]], [[5uci]], [[5ucj]], [[4o04]], [[4o05]], **[[4o07]] - hHsp90-b NTD + inhibitor<br />
**[[3nmq]] - hHsp90 NTD+pyrimidine derivative
**[[3nmq]] - hHsp90 NTD+pyrimidine derivative
**[[3pry]] – hHsp90 MD<br />
**[[3pry]] – hHsp90 MD<br />
 +
**[[7zub]] - hHsp90 + AIP + AH receptor + ADP - Cryo EM <br />
 +
**[[8e0a]] - hHsp90 + AIPL1 + ANP – Cryo EM <br />
 +
**[[7z37]], [[7z38]] - hHsp90 + Cdc37 + RAF-1 – Cryo EM <br />
 +
**[[8gae]] - hHsp90 + Cdc37 + RAF-1 + PP5 – Cryo EM <br />
 +
**[[7zr0]] - hHsp90 + Cdc37 + BRAF – Cryo EM <br />
 +
**[[7zr5]], [[7zr6]] - hHsp90 + Cdc37 + BRAF + PP5 – Cryo EM <br />
 +
**[[7y04]] - mHsp90 + AH receptor + P23 + ADP - mouse - Cryo EM <br />
* Hsp82 is the yeast equivalent of Hsp90 in mammals
* Hsp82 is the yeast equivalent of Hsp90 in mammals
Line 331: Line 368:
**[[1khy]] – EcClpB NTD <br />
**[[1khy]] – EcClpB NTD <br />
**[[1jbk]] – EcClpB nucleotide binding domain 1<br />
**[[1jbk]] – EcClpB nucleotide binding domain 1<br />
 +
**[[1yg6]] – EcClpP<br />
 +
**[[1yg8]], [[3hln]] – EcClpP (mutant)<br />
 +
**[[2fzs]], [[7mk5]] – EcClpP + inhibitor<br />
 +
**[[6nb1]] – EcClpP + activator<br />
 +
**[[3mt6]] – EcClpP + Adep1<br />
 +
**[[6wr2]], [[6wsg]] – EcClpP + ClpX – Cryo EM<br />
 +
**[[6wrf]] – EcClpP + ClpX + GFP – Cryo EM<br />
 +
**[[8et3]] – EcClpP + ClpX + GFP + SSPB – Cryo EM<br />
**[[4iod]], [[4irf]] - PfClpB <br />
**[[4iod]], [[4irf]] - PfClpB <br />
**[[1qvr]] - TtClpB <br />
**[[1qvr]] - TtClpB <br />
Line 356: Line 401:
**[[7m1l]], [[7m1m]] – ClpP2 – ''Pseudomonas aeruginosa''<br />
**[[7m1l]], [[7m1m]] – ClpP2 – ''Pseudomonas aeruginosa''<br />
**[[6cfd]] – ClpP + antibiotic – ''Enterococcus faecium''<br />
**[[6cfd]] – ClpP + antibiotic – ''Enterococcus faecium''<br />
 +
**[[7tfm]] – ClpP N-domain – ''Leishmania mexicana''<br />
*Hsp101
*Hsp101
Line 374: Line 420:
**[[5zui]] – ChtHsp104 – ''Chaetomium thermophilum''<br />
**[[5zui]] – ChtHsp104 – ''Chaetomium thermophilum''<br />
**[[7cg3]] – ChtHsp104 - Cryo EM<br />
**[[7cg3]] – ChtHsp104 - Cryo EM<br />
 +
**[[5d4w]] – ChtHsp104 (mutant)<br />
* Hsp110 in mammals is named Sse1, Sse2 in yeast
* Hsp110 in mammals is named Sse1, Sse2 in yeast
Line 411: Line 458:
**[[5ycq]] – EcHspQ<br />
**[[5ycq]] – EcHspQ<br />
 +
 +
*Hsp DegP or Periplasmic serine endoprotease DegP; Domains PDZ1 38-385; PDZ2 400-474
 +
 +
**[[3mh4]] – EcDegP <br />
 +
**[[1ky9]] – EcDegP (mutant) <br />
 +
**[[8f0a]], [[8f0u]], [[8f1t]], [[8f1u]], [[8f21]] – EcDegP + telomeric repeat-binding factor peptide – Cryo EM<br />
 +
**[[2zle]], [[4a8d]] – EcDegP + OmpC – Cryo EM<br />
 +
**[[3cs0]], [[3mh5]], [[3mh6]], [[3mh7]], [[3ou0]], [[6jjk]], [[6jjl]], [[6jjo]] – EcDegP + peptide <br />
 +
**[[3otp]] – EcDegP + lysozyme <br />
*'''Heat shock cognate protein (Hsc)'''
*'''Heat shock cognate protein (Hsc)'''
Line 438: Line 494:
**[[2v7z]] – rHsc70 NBD + SBD – rat<br />
**[[2v7z]] – rHsc70 NBD + SBD – rat<br />
**[[7hsc]], [[1ckr]] - rHsc70 sub - NMR<br />
**[[7hsc]], [[1ckr]] - rHsc70 sub - NMR<br />
-
**[[3cqx]] - Hsc70 NBD+BAG domain regulator protein – mouse<br />
+
**[[3cqx]] - Hsc70 NBD+BAG domain regulator protein <br />
*''Hsc82''
*''Hsc82''
Line 445: Line 501:
**[[6xlh]] - yHsc82 MD+co-chaperone AHA1 + ADP + ATPgS<br />
**[[6xlh]] - yHsc82 MD+co-chaperone AHA1 + ADP + ATPgS<br />
**[[6xld]], [[6xle]], [[6xlf]] - yHsc82 MD+co-chaperone AHA1 + ANP <br />
**[[6xld]], [[6xle]], [[6xlf]] - yHsc82 MD+co-chaperone AHA1 + ANP <br />
 +
**[[6xlb]] - yHsc82 MD+co-chaperone AHA1 + ANP – Cryo EM<br />
**[[6xlg]] - yHsc82 MD+co-chaperone AHA1 + ATPgS<br />
**[[6xlg]] - yHsc82 MD+co-chaperone AHA1 + ATPgS<br />

Revision as of 07:46, 1 May 2023

3D Structures of Heat Shock Proteins

Updated on 01-May-2023

Hsp90-a NTD+linker residues 1-293

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky

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