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Journal:Proteins:3

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==Do ''Newly Born'' orphan proteins resemble ''Never Born'' proteins? A study using three deep learning algorithms==
==Do ''Newly Born'' orphan proteins resemble ''Never Born'' proteins? A study using three deep learning algorithms==
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<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='96/964832/Hco_af2_top_model/1'>
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<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='96/964832/Hco_af2_top_model/2'>
''Newly Born'' proteins, or orphan proteins, have no sequence homology to other proteins and occur in single species or within a taxonomically restricted gene family
''Newly Born'' proteins, or orphan proteins, have no sequence homology to other proteins and occur in single species or within a taxonomically restricted gene family

Revision as of 15:03, 3 May 2023

Do Newly Born orphan proteins resemble Never Born proteins? A study using three deep learning algorithms

Caption for this structure

Drag the structure with the mouse to rotate

References

  1. Tretyachenko V, Vymětal J, Bednárová L, Kopecký V Jr, Hofbauerová K, Jindrová H, Hubálek M, Souček R, Konvalinka J, Vondrášek J, Hlouchová K. Random protein sequences can form defined secondary structures and are well-tolerated in vivo. Sci Rep. 2017 Nov 13;7(1):15449. PMID:29133927 doi:10.1038/s41598-017-15635-8
  2. Dunker AK, Silman I, Uversky VN, Sussman JL. Function and structure of inherently disordered proteins. Curr Opin Struct Biol. 2008 Dec;18(6):756-64. Epub 2008 Nov 17. PMID:18952168 doi:10.1016/j.sbi.2008.10.002
  3. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  4. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman, Jaime Prilusky

This page complements a publication in scientific journals and is one of the Proteopedia's Interactive 3D Complement pages. For aditional details please see I3DC.
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