This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Hexokinase 3D structures
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 7: | Line 7: | ||
**[[3o08]], [[3o1b]], [[3o1w]], [[3o4w]], [[3o6w]], [[3o80]], [[4jax]] – KlHK – ''Kluyveromyces lactis''<br /> | **[[3o08]], [[3o1b]], [[3o1w]], [[3o4w]], [[3o6w]], [[3o80]], [[4jax]] – KlHK – ''Kluyveromyces lactis''<br /> | ||
| + | **[[6vyf]], [[6vyg]] - HK – ''Plasmodium vivax'' – Cryo EM<br /> | ||
**[[2e2n]] – StHK – ''Sulfolobus tokodaii''<br /> | **[[2e2n]] – StHK – ''Sulfolobus tokodaii''<br /> | ||
**[[2e2o]] - StHK + glucose<br /> | **[[2e2o]] - StHK + glucose<br /> | ||
| Line 12: | Line 13: | ||
**[[2e2q]] - StHK + ADP + xylose + Mg<br /> | **[[2e2q]] - StHK + ADP + xylose + Mg<br /> | ||
**[[3o5b]], [[3o8m]] – KlHK + glucose<br /> | **[[3o5b]], [[3o8m]] – KlHK + glucose<br /> | ||
| - | **[[1bdg]] – HK + glucose – ''Schistosoma mansoni'' | + | **[[1bdg]] – HK + glucose – ''Schistosoma mansoni''<br /> |
| + | **[[6krj]], [[6ksr]] - HK – ''Eimeria tenella''<br /> | ||
| + | **[[6da0]] - HK – ''Naegleria fowleri''<br /> | ||
| + | **[[6edi]] - HK – ''Leishmania braziliensis''<br /> | ||
*Hexokinase I | *Hexokinase I | ||
| Line 18: | Line 22: | ||
**[[1dgk]] – hHK I (mutant) + ADP + glucose – human<br /> | **[[1dgk]] – hHK I (mutant) + ADP + glucose – human<br /> | ||
**[[1cza]] - hHK I (mutant) + ADP + glucose-6-phosphate + glucose<br /> | **[[1cza]] - hHK I (mutant) + ADP + glucose-6-phosphate + glucose<br /> | ||
| - | **[[1bg3]] - raHK I + glucose-6-phosphate + glucose - rat<br /> | ||
**[[1qha]] – hHK I + AMP-PNP<br /> | **[[1qha]] – hHK I + AMP-PNP<br /> | ||
**[[1hkc]] - hHK I + phosphate + glucose<br /> | **[[1hkc]] - hHK I + phosphate + glucose<br /> | ||
| Line 26: | Line 29: | ||
**[[4foi]] - hHK I (mutant) + glucose 1,6-bisphosphate + glucose<br /> | **[[4foi]] - hHK I (mutant) + glucose 1,6-bisphosphate + glucose<br /> | ||
**[[4fpb]] - hHK I + 1,5-anhydroglucitol-6-phosphate + glucose<br /> | **[[4fpb]] - hHK I + 1,5-anhydroglucitol-6-phosphate + glucose<br /> | ||
| + | **[[1bg3]] - raHK I + glucose-6-phosphate + glucose - rat<br /> | ||
**[[4qs8]] - AtHK I – ''Arabidopsis thaliana''<br /> | **[[4qs8]] - AtHK I – ''Arabidopsis thaliana''<br /> | ||
**[[4qs7]] - AtHK I + glucose <br /> | **[[4qs7]] - AtHK I + glucose <br /> | ||
**[[4qs9]] - AtHK I (mutant) + glucose <br /> | **[[4qs9]] - AtHK I (mutant) + glucose <br /> | ||
**[[3b8a]] – yHK I + glucose – yeast<br /> | **[[3b8a]] – yHK I + glucose – yeast<br /> | ||
| - | **[[1hkg]] – yHK I<br /> | + | **[[1hkg]], [[6p4x]] – yHK I<br /> |
| + | **[[6pdt]] – yHK I + glucopyranose – Cryo EM<br /> | ||
| + | **[[6r2n]] - KlHK I <br /> | ||
*Hexokinase II or HK VI | *Hexokinase II or HK VI | ||
| Line 47: | Line 53: | ||
*Hexokinase IV (Glucokinase GK) | *Hexokinase IV (Glucokinase GK) | ||
| - | **[[3qic]] – | + | **[[3qic]] – hGK IV residues 12-465 (mutant) <br /> |
**[[1v4t]] – hGK <br /> | **[[1v4t]] – hGK <br /> | ||
**[[3mcp]] – GK – ''Parabacterioides distasonis''<br /> | **[[3mcp]] – GK – ''Parabacterioides distasonis''<br /> | ||
| Line 58: | Line 64: | ||
*''Hexokinase IV binary complex'' | *''Hexokinase IV binary complex'' | ||
| - | **[[3idh]] - | + | **[[3idh]] - hGK IV residues 12-465 + glucose<br /> |
| - | **[[3h1v]], [[3imx]], [[3a0i]], [[3goi]],[[1v4s]], [[3s41]], [[3vev]], [[3vf6]], [[4dch]], [[4dhy]] - | + | **[[3h1v]], [[3imx]], [[3a0i]], [[3goi]],[[1v4s]], [[3s41]], [[3vev]], [[3vf6]], [[4dch]], [[4dhy]] - hGK IV residues 12-465 + synthetic activator<br /> |
| - | **[[3fr0]], [[4l3q]], [[4ise]], [[4isf]], [[4isg]], [[4iwv]], [[4ixc]], [[4mlh]], [[4mle]], [[5v4w]], [[5v4x]] - | + | **[[3fr0]], [[4l3q]], [[4ise]], [[4isf]], [[4isg]], [[4iwv]], [[4ixc]], [[4mlh]], [[4mle]], [[5v4w]], [[5v4x]], [[6e0e]], [[6e0i]] - hGK IV residues 12-465 + activator<br /> |
**[[1sz2]] - EcGK + glucose<br /> | **[[1sz2]] - EcGK + glucose<br /> | ||
**[[3vgm]] - SgGK + glucose<br /> | **[[3vgm]] - SgGK + glucose<br /> | ||
| Line 67: | Line 73: | ||
**[[3vey]] - hGK + glucose + ATPgS<br /> | **[[3vey]] - hGK + glucose + ATPgS<br /> | ||
| - | **[[3id8]], [[3fgu]] - | + | **[[7t78]], [[7t79]] - hGK IV + glucose + ligand<br /> |
| - | **[[3f9m]], [[4l3q]], [[4no7]], [[4rch]] - | + | **[[3id8]], [[3fgu]] - hGK IV residues 12-465 + AMP-PNP + glucose<br /> |
| + | **[[3f9m]], [[4l3q]], [[4no7]], [[4rch]] - hGK IV residues 12-465 + activator + glucose<br /> | ||
**[[4lc9]], [[3w0l]] – raGK + fructose-6-phosphate + GK regulator<br /> | **[[4lc9]], [[3w0l]] – raGK + fructose-6-phosphate + GK regulator<br /> | ||
**[[2q2r]] - GK + glucose + ADP – ''Trypanosoma cruzi''<br /> | **[[2q2r]] - GK + glucose + ADP – ''Trypanosoma cruzi''<br /> | ||
Current revision
3D structures of hexokinase
Updated on 16-May-2023
