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Histone acetyltransferase 3D structures

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(New page: == 3D Structures of histone acetyltransferase == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Histone acetyltra...)
Current revision (07:49, 21 May 2023) (edit) (undo)
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
-
*Histone acetyltransferase; Human domains – HAT 170-458; catalytic 497-662; bromodomain 729-837;
+
*Histone acetyltransferase; Human domains – WH 100-182; DPF 194-323; HAT 170-458; catalytic 497-662; bromodomain 729-837;
**[[1f68]] – hHAT bromodomain (mutant) – human – NMR
**[[1f68]] – hHAT bromodomain (mutant) – human – NMR
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**[[2ln0]] - hHAT KAT6A<br />
**[[2ln0]] - hHAT KAT6A<br />
**[[4ljn]] - hHAT KAT6A double PHD finger<br />
**[[4ljn]] - hHAT KAT6A double PHD finger<br />
 +
**[[8e4v]] - hHAT KAT6B WH domain - NMR<br />
**[[5wci]] - hHAT KAT8 HAT domain <br />
**[[5wci]] - hHAT KAT8 HAT domain <br />
 +
**[[7cmr]] - hHAT KAT8 1-458 <br />
**[[5j8c]], [[5j8f]] - hHAT KAT8 HAT domain (mutant)<br />
**[[5j8c]], [[5j8f]] - hHAT KAT8 HAT domain (mutant)<br />
 +
**[[7by1]] - mHAT KAT2A N-terminal 67-378 - mouse<br />
**[[1qso]] - yHAT HPA2 – yeast<br />
**[[1qso]] - yHAT HPA2 – yeast<br />
**[[3to7]] – yHAT Esa1<br />
**[[3to7]] – yHAT Esa1<br />
**[[2rnz]] – yHAT Esa1 chromodomain – NMR
**[[2rnz]] – yHAT Esa1 chromodomain – NMR
- 
**[[2ro0]] - yHAT Esa1 knotted Tudor domain – NMR<br />
**[[2ro0]] - yHAT Esa1 knotted Tudor domain – NMR<br />
**[[1ygh]] – yHAT HAT domain<br />
**[[1ygh]] – yHAT HAT domain<br />
 +
**[[6s1l]] – fyHAT B subunit 2 – fission yeast <br />
**[[2qec]] – HAT HPA2 (mutant) – ''Corynebacterium glutamicum''<br />
**[[2qec]] – HAT HPA2 (mutant) – ''Corynebacterium glutamicum''<br />
**[[6ia8]], [[6iad]], [[6iaz]] - HAT – ''Methanocaldococcus infernus''<br />
**[[6ia8]], [[6iad]], [[6iaz]] - HAT – ''Methanocaldococcus infernus''<br />
 +
**[[6if4]] - HAT – ''Trypanosoma brucei''<br />
 +
**[[7bwz]], [[7bx0]], [[7bx1]], [[7bxw]], [[7c3o]] - HAT RTT109 – ''Candida albicans''<br />
*Histone acetyltransferase binary complexes
*Histone acetyltransferase binary complexes
Line 54: Line 59:
**[[5lvq]], [[5lvr]], [[5fdz]], [[5fe0]], [[5fe1]], [[5fe2]], [[5fe3]], [[5fe4]], [[5fe5]], [[5fe6]], [[5fe7]], [[5fe8]], [[5fe9]], [[5mkx]] - hHAT KAT2B bromodomain + inhibitor<br />
**[[5lvq]], [[5lvr]], [[5fdz]], [[5fe0]], [[5fe1]], [[5fe2]], [[5fe3]], [[5fe4]], [[5fe5]], [[5fe6]], [[5fe7]], [[5fe8]], [[5fe9]], [[5mkx]] - hHAT KAT2B bromodomain + inhibitor<br />
**[[4dnc]] – hHAT KAT8 HAT domain + male-specific lethal 1 homolog<br />
**[[4dnc]] – hHAT KAT8 HAT domain + male-specific lethal 1 homolog<br />
-
**[[3v43]], [[4lk9]], [[4lka]], [[4llb]], [[5b75]], [[5b76]], [[5b77]], [[5b78]] - hHAT KAT6A + H3.1 peptide<br />
+
**[[3v43]], [[4lk9]], [[4lka]], [[4llb]], [[5b75]], [[5b76]], [[5b77]], [[5b78]], [[6lsb]] - hHAT KAT6A + H3.1 peptide<br />
-
**[[5u2j]] - hHAT KAT6B + H3K14BU peptide<br />
+
**[[7y43]], [[8h7a]] - hHAT KAT6A + DNA<br />
-
**[[5gk9]] - hHAT KAT7 + BRD1<br />
+
**[[5u2j]], [[6oie]] - hHAT KAT6B + H3K14BU peptide<br />
-
**[[5ml0]] - HAT KAT2B bromodomain + inhibitor - mouse<br />
+
**[[5gk9]], [[6maj]], [[6mak]], [[7d0o]] - hHAT KAT7 + BRD1<br />
 +
**[[4dnc]] – hHAT KAT8 HAT domain + male-specific lethal 1 homolog<br />
 +
**[[6ct2]], [[6ba2]] – hHAT KAT8 HAT domain + inhibitor<br />
 +
**[[6oin]], [[6oio]], [[6oip]], [[6oir]], [[6owh]], [[6owi]], [[6pd8]], [[6pd9]], [[6pda]], [[6pdb]], [[6pdc]], [[6pdd]], [[6pde]], [[6pdf]], [[6pdg]] – hHAT KAT8 HAT domain (mutant) + inhibitor<br />
 +
**[[5h86]], [[6ba4]] - hHAT KAT8 HAT domain + acetyl CoA<br />
 +
**[[7kpy]] - hHAT 617-732 + inhibitor <br />
 +
**[[7qgs]] - hHAT 330-440 + MRG-1<br />
 +
**[[5ml0]] - mHAT KAT2B bromodomain + inhibitor<br />
**[[1bob]] – yHAT 1 + acetyl-CoA
**[[1bob]] – yHAT 1 + acetyl-CoA
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**[[3qm0]] - yHAT RTT109 (mutant) + acetyl-CoA
**[[3qm0]] - yHAT RTT109 (mutant) + acetyl-CoA
-
**[[3q35]], [[3q66]], [[3q68]] – yHAT RTT109 + vacuolar protein sorting-associated protein 75
+
**[[3q35]], [[3q66]], [[3q68]] – yHAT RTT109 + vacuolar protein sorting-associated protein 75<br />
-
 
+
**[[6s1r]] – fyHAT B subunit 2 + histone H4<br />
 +
**[[6s29]] – fyHAT B subunit 2 + Mis19<br />
**[[5gcn]] – TtHAT Gcn5 + CoA – ''Tetrahymena thermophila'' - NMR<br />
**[[5gcn]] – TtHAT Gcn5 + CoA – ''Tetrahymena thermophila'' - NMR<br />
**[[5tpx]] - HAT GCN5 + probe – ''Plasmodium falciparum''<br />
**[[5tpx]] - HAT GCN5 + probe – ''Plasmodium falciparum''<br />
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*Histone acetyltransferase ternary complexes
*Histone acetyltransferase ternary complexes
 +
**[[6vo5]] – hHAT B catalytic subunit + histone H4 + CoA derivative<br />
 +
**[[7d0p]], [[7d0q]], [[7d0r]], [[7d0s]] - hHAT KAT7 + BRD1 + CoA derivative<br />
**[[3q33]] – yHAT RTT109 + vacuolar protein sorting-associated protein 75 + histone H3 peptide<br />
**[[3q33]] – yHAT RTT109 + vacuolar protein sorting-associated protein 75 + histone H3 peptide<br />
 +
**[[7xay]] – yHAT1 + HAT2 + ASF1 + histone H3 + histone H4 <br />
 +
**[[6o22]] - yHAT RTT109 + vacuolar protein sorting-associated protein 75 + ASF1 + histone H3.2 + histone H4 – NMR<br />
**[[4psx]] - yHAT B + H3 peptide + H4 peptide<br />
**[[4psx]] - yHAT B + H3 peptide + H4 peptide<br />
**[[5j9q]], [[5j9t]], [[5j9u]], [[5j9w]] - yHAT Esa1 (mutant) + chromatin modification-related protein + enhancer of polycomb-like protein<br />
**[[5j9q]], [[5j9t]], [[5j9u]], [[5j9w]] - yHAT Esa1 (mutant) + chromatin modification-related protein + enhancer of polycomb-like protein<br />
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**[[3i3j]] – hHAT P300 bromodomain <br />
**[[3i3j]] – hHAT P300 bromodomain <br />
 +
**[[7uge]], [[7ugi]], [[7ugl]] - hHAT P300 bromodomain + inhibitor <br />
**[[3io2]] – hHAT P300 TAZ2 domain <br />
**[[3io2]] – hHAT P300 TAZ2 domain <br />
 +
**[[6fgn]], [[6fgs]] - hHAT TAZ2 domain - NMR<br />
 +
**[[2mzd]] - hHAT TAZ2 domain (mutant) + p53 peptide - NMR<br />
**[[4bhw]] - hHAT P300 core (mutant)<br />
**[[4bhw]] - hHAT P300 core (mutant)<br />
**[[6k4n]] - hHAT P300 bromodomain+acetyltransferase domains – Cryo EM<br />
**[[6k4n]] - hHAT P300 bromodomain+acetyltransferase domains – Cryo EM<br />
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**[[5lkz]] - hHAT P300 core (mutant) + crotonyl CoA<br />
**[[5lkz]] - hHAT P300 core (mutant) + crotonyl CoA<br />
**[[3biy]] – hHAT P300 acetyltransferase domain + lysine CoA derivative<br />
**[[3biy]] – hHAT P300 acetyltransferase domain + lysine CoA derivative<br />
-
**[[5kj2]] - hHAT P300 acetyltransferase domain + inhibitor<br />
+
**[[5kj2]], [[7lje]] - hHAT P300 acetyltransferase domain + inhibitor<br />
 +
**[[6pf1]], [[6v8b]], [[6v8k]], [[6v8n]], [[6v90]], [[7ss8]], [[7ssk]], [[7szq]], [[7vhy]], [[7vhz]], [[7vi0]], [[8gzc]] - hHAT P300 acetyltransferase domain (mutant) + inhibitor<br />
 +
**[[6pgu]] - hHAT P300 acetyltransferase domain (mutant) + inhibitor + CoA<br />
**[[6gyr]] - hHAT P300 core+acetyltransferase domains + lysine CoA derivative<br />
**[[6gyr]] - hHAT P300 core+acetyltransferase domains + lysine CoA derivative<br />
**[[5xzc]] - hHAT P300 core+acetyltransferase domains + p53<br />
**[[5xzc]] - hHAT P300 core+acetyltransferase domains + p53<br />
**[[5bt3]], [[5nu5]], [[5lpk]], [[5lpm]] - hHAT P300 bromodomain + inhibitor<br />
**[[5bt3]], [[5nu5]], [[5lpk]], [[5lpm]] - hHAT P300 bromodomain + inhibitor<br />
**[[6gyt]] - hHAT P300 bromodomain + histone H4 peptide<br />
**[[6gyt]] - hHAT P300 bromodomain + histone H4 peptide<br />
 +
**[[7w9v]], [[8hag]], [[8hah]], [[8hai]], [[8haj]], [[8hak]] - hHAT P300 1098-1836 + nucleosome – Cryo EM<br />
**[[3p57]] - hHAT P300 TAZ2 domain + myocyte-specific enhancer factor 2A + DNA
**[[3p57]] - hHAT P300 TAZ2 domain + myocyte-specific enhancer factor 2A + DNA
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of histone acetyltransferase

Updated on 21-May-2023

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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