This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Integrin 3D structures

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:32, 31 May 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 8: Line 8:
**[[1ido]] – hIG I domain + Mg – human<br />
**[[1ido]] – hIG I domain + Mg – human<br />
**[[1jlm]] - hIG I domain + Mn<br />
**[[1jlm]] - hIG I domain + Mn<br />
- 
-
*IG CD11a or IG α-L
 
- 
-
**[[1lfa]] - hIG I domain + Mn<br />
 
-
**[[1zon]] - hIG I domain<br />
 
-
**[[1zoo]], [[1zop]], [[3f74]] - hIG I domain + Mg<br />
 
-
**[[1mq9]] - hIG I domain (mutant) + Mn<br />
 
-
**[[1mjn]] - hIG I domain (mutant) + Mg<br />
 
-
**[[1mqa]] - hIG I domain (mutant) <br />
 
-
**[[2k8o]] – hIG cytoplasmic domain (mutant) – NMR<BR />
 
- 
-
*''IG CD11a complexes''
 
- 
-
**[[1cqp]] - hIG I domain + lovastatin + Mg<br />
 
-
**[[1mq8]], [[3bn3]], [[3tcx]] - hIG I domain (mutant) + intracellular adhesion molecule + Mg<br />
 
-
**[[1t0p]] - hIG I domain + intracellular adhesion molecule-3 + Mg<br />
 
-
**[[1rd4]], [[2ica]], [[3bqm]], [[3bqn]], [[3e2m]] - hIG I domain + inhibitor<br />
 
-
**[[2o7n]], [[3m6f]] - hIG I domain + antagonist<br />
 
-
**[[1xdd]], [[1xdg]], [[1xuo]] - hIG I domain + inhibitor + Mg<br />
 
-
**[[4ixd]] - hIG I domain + activator + Mg<br />
 
-
**[[3f78]] - hIG I domain + anesthetic + Mg<br />
 
-
**[[3eoa]], [[3eob]] - hIG I domain + antibody<br />
 
-
**[[3hi6]] - hIG I domain (mutant) + antibody + Mn<br />
 
- 
-
*IG CD11b I domain 143-337 or IG α-M
 
- 
-
**[[1idn]], [[1na5]] - hIG<br />
 
-
**[[1mf7]] - hIG (mutant)<br />
 
-
**[[1bho]] - hIG + Mg<br />
 
-
**[[1bhq]] - hIG + Cd<br />
 
-
**[[1m1u]] - hIG (mutant) + Ca<br />
 
-
**[[1n9z]] - hIG (mutant) + Mg<br />
 
-
**[[3q3g]], [[3qa3]] – hIG + antibody<br />
 
-
**[[4m76]] – hIG + complement C3<br />
 
-
**[[2lke]], [[2lkj – hIG cytoplasmic domain – NMR<br />
 
-
**[[4xw2]] – hIG + simvastatin<br />
 
-
**[[6rhv]], [[6rhw]] – hIG + cytolysin<br />
 
- 
-
*IG CD11c
 
- 
-
**[[1n3y]] - hIG I domain (mutant)
 
*IG α-1 (CD49a)
*IG α-1 (CD49a)
Line 71: Line 30:
**[[2k1a]] - hIG transmembrane domain – NMR<BR />
**[[2k1a]] - hIG transmembrane domain – NMR<BR />
-
*IG α-1 β-1 (CD49a-CD49b)
+
*IG α-1 + IG β-1 (CD49a-CD49b)
**[[1qc5]], [[1qcy]] - hIG I domain (mutant) + Mg<br />
**[[1qc5]], [[1qcy]] - hIG I domain (mutant) + Mg<br />
**[[1pt6]] - hIG I domain + Mg<br />
**[[1pt6]] - hIG I domain + Mg<br />
-
*IG α-2 (CD49b) β
+
*IG α-2 (CD49b) + IG β
**[[5hj2]] - hIG I domain<br />
**[[5hj2]] - hIG I domain<br />
Line 82: Line 41:
**[[2k1a]] - hIG transmembrane domain – NMR<br />
**[[2k1a]] - hIG transmembrane domain – NMR<br />
-
*IG α-2b β-3 (CD61)
+
*IG α-2b + IG β-3 (CD61)
**[[1kup]], [[1kuz]] – hIG proximal domain – NMR<BR />
**[[1kup]], [[1kuz]] – hIG proximal domain – NMR<BR />
**[[1m8o]] - hIG cytoplasmic domain – NMR<BR />
**[[1m8o]] - hIG cytoplasmic domain – NMR<BR />
**[[4cak]] – hIG – Cryo-EM<br />
**[[4cak]] – hIG – Cryo-EM<br />
-
**[[2k9j]], [[2knc]] - hIG transmembrane domain – NMR<BR />
+
**[[2k9j]], [[2knc]], [[7kn0]] - hIG transmembrane domain – NMR<BR />
**[[1tye]], [[3fcu]], [[3fcs]] – hIG + Mg<br />
**[[1tye]], [[3fcu]], [[3fcs]] – hIG + Mg<br />
**[[3fc3]] – hIG (mutant) + Mg<br />
**[[3fc3]] – hIG (mutant) + Mg<br />
Line 94: Line 53:
**[[2vdm]], [[2vdn]], [[3t3m]], [[3t3p]] – hIG headpiece + antibody + antagonist + Mg<br />
**[[2vdm]], [[2vdn]], [[3t3m]], [[3t3p]] – hIG headpiece + antibody + antagonist + Mg<br />
**[[2vdo]], [[2vdp]], [[2vdq]], [[2vdr]] – hIG headpiece + antibody + fibrinogen peptide + Mg<br />
**[[2vdo]], [[2vdp]], [[2vdq]], [[2vdr]] – hIG headpiece + antibody + fibrinogen peptide + Mg<br />
-
**[[6v4p]] – hIG + antibody – Cryo-EM<br />
+
**[[6v4p]], [[7la4]] – hIG + antibody – Cryo-EM<br />
 +
**[[7l8p]], [[7tct]], [[7td8]], [[7tho]], [[7tmz]], [[7tpd]], [[7u60]], [[7u9f]], [[7u9v]], [[7ubr]], [[7ucy]], [[7udg]], [[7udh]], [[7ue0]], [[7ufh]], [[7uh8]], [[7uje]], [[7ujk]], [[7uk9]], [[7uko]], [[7ukp]], [[7ukt]] – hIG + antibody + drug<br />
*IG α-4
*IG α-4
Line 100: Line 60:
**[[4irz]] - hIG + antibody <br />
**[[4irz]] - hIG + antibody <br />
-
*IG α-4 (CD49d) β-7
+
*IG α-4 (CD49d) + IG β-7
**[[3v4p]] - hIG headpiece (mutant) + antibody + Mg<br />
**[[3v4p]] - hIG headpiece (mutant) + antibody + Mg<br />
**[[3v4v]] - hIG headpiece (mutant) + antibody + inhibitor + Mg<br />
**[[3v4v]] - hIG headpiece (mutant) + antibody + inhibitor + Mg<br />
-
*IG α-5 (CD49e) β-1 (CD29)
+
*IG α-5 (CD49e) + IG β-1 (CD29)
 +
**[[7nxd]] – hIG + Mg – Cryo-EM<br />
 +
**[[7nwl]] – hIG + fibronectin + laminin – Cryo-EM<br />
**[[4wjk]] - hIG headpiece (mutant) + Mg<br />
**[[4wjk]] - hIG headpiece (mutant) + Mg<br />
**[[4wk0]], [[4wk2]], [[4wk4]] - hIG headpiece (mutant) + peptide + Mg<br />
**[[4wk0]], [[4wk2]], [[4wk4]] - hIG headpiece (mutant) + peptide + Mg<br />
Line 112: Line 74:
**[[3vi4]] - hIG headpiece + antibody + peptide + Mg<br />
**[[3vi4]] - hIG headpiece + antibody + peptide + Mg<br />
-
*IG α-5 (CD49e) β-3 (CD61) ectodomain
+
*IG α-5 (CD49e) + IG β-3 (CD61) ectodomain
**[[3ije]], [[1m1x]], [[4g1e]], [[4g1m]], [[1u8c]] – hIG + cation<br />
**[[3ije]], [[1m1x]], [[4g1e]], [[4g1m]], [[1u8c]] – hIG + cation<br />
Line 120: Line 82:
**[[1l5g]] - hIG + tripeptide + Mn<br />
**[[1l5g]] - hIG + tripeptide + Mn<br />
-
*IG α-5 β-6
+
*IG α-5 + IG β-6
**[[4um8]] – hIG headpiece (mutant) + Ni<br />
**[[4um8]] – hIG headpiece (mutant) + Ni<br />
Line 127: Line 89:
**[[5neu]], [[5net]], [[5ner]], [[5nem]] – hIG headpiece + foot-and-mouth virus – Cryo EM<br />
**[[5neu]], [[5net]], [[5ner]], [[5nem]] – hIG headpiece + foot-and-mouth virus – Cryo EM<br />
**[[5ffo]] – hIG headpiece + TGF-beta-1<br />
**[[5ffo]] – hIG headpiece + TGF-beta-1<br />
 +
 +
*IG α-6 + IG β-1
 +
**[[7ceb]], [[7cec]] – hIG headpiece + laminin + Mg<br />
*IG α-L
*IG α-L
-
**[[4ixd]] – hIG I domain<br />
+
**[[1lfa]] - hIG I domain + Mn <br />
 +
**[[1zon]], [[4ixd]], [[7kc3]] - hIG I domain 153-334 <br />
 +
**[[1mqa]] - hIG I domain (mutant) <br />
 +
**[[1zoo]], [[1zop]], [[3f74]] - hIG I domain + Mg <br />
 +
**[[1mq9]] - hIG I domain (mutant) + Mn <br />
 +
**[[1mjn]] - hIG I domain (mutant) + Mg <br />
 +
**[[2k8o]] – hIG cytoplasmic domain (mutant) – NMR <br />
**[[5e6s]], [[5e6r]] – hIG AI, headpiece,pocket domains + Mg<br />
**[[5e6s]], [[5e6r]] – hIG AI, headpiece,pocket domains + Mg<br />
**[[2m3e]] – hIG transmembrane domain - NMR<br />
**[[2m3e]] – hIG transmembrane domain - NMR<br />
-
*IG α-L β-2
+
*IG α-L complexes
 +
 
 +
**[[1cqp]] - hIG I domain + lovastatin + Mg <br />
 +
**[[1mq8]], [[3bn3]], [[3tcx]] - hIG I domain (mutant) + intracellular adhesion molecule + Mg <br />
 +
**[[1t0p]] - hIG I domain + intracellular adhesion molecule-3 + Mg<br />
 +
**[[1rd4]], [[2ica]], [[3bqm]], [[3bqn]], [[3e2m]] - hIG I domain + inhibitor<br />
 +
**[[2o7n]], [[3m6f]] - hIG I domain + antagonist<br />
 +
**[[1xdd]], [[1xdg]], [[1xuo]], [[7kc5]] - hIG I domain + inhibitor + Mg<br />
 +
**[[7kc6]] - hIG I domain + drug + Mg<br />
 +
**[[3f78]] - hIG I domain + anesthetic + Mg<br />
 +
**[[3eoa]], [[3eob]] - hIG I domain + antibody<br />
 +
**[[3hi6]] - hIG I domain (mutant) + antibody + Mn<br />
 +
 
 +
*IG α-L + IG β-2
**[[5e6u]] – hIG headpiece (mutant) + Ni<br />
**[[5e6u]] – hIG headpiece (mutant) + Ni<br />
-
*IG α-V β-3
+
*IG α-M
 +
 
 +
**[[1idn]], [[1na5]] - hIG<br />
 +
**[[1mf7]] - hIG (mutant) <br />
 +
**[[1bho]] - hIG + Mg<br />
 +
**[[1bhq]] - hIG + Cd<br />
 +
**[[1m1u]] - hIG (mutant) + Ca<br />
 +
**[[1n9z]] - hIG (mutant) + Mg<br />
 +
**[[3q3g]], [[3qa3]] – hIG + antibody<br />
 +
**[[4m76]] – hIG + complement C3<br />
 +
**[[2lke]], [[2lkj]] – hIG cytoplasmic domain – NMR<br />
 +
**[[4xw2]] – hIG + simvastatin<br />
 +
**[[6rhv]], [[6rhw]] – hIG + cytolysin<br />
 +
 
 +
*IG α-M + IG β-2
 +
 
 +
**[[7usm]] – hIG ectodomain – Cryo EM<br />
 +
**[[7usl]] – hIG ectodomain + adenylate cyclase toxin + antibody – Cryo EM<br />
 +
**[[7p2d]] – hIG ectodomain + nanobody <br />
 +
 
 +
*IG α-V + IG β-3
**[[6mk0]] – hIG + antagonist<br />
**[[6mk0]] – hIG + antagonist<br />
Line 145: Line 149:
**[[6naj]] – hIG + fibronectin<br />
**[[6naj]] – hIG + fibronectin<br />
-
*IG α-V β-8
+
*IG α-V + IG β-8
**[[6djp]], [[6ujb]], [[6ujc]] – hIG + antibody – Cryo EM<br />
**[[6djp]], [[6ujb]], [[6ujc]] – hIG + antibody – Cryo EM<br />
Line 151: Line 155:
**[[6om2]] – hIG (mutant) + Protgf-b1 RGD peptide<br />
**[[6om2]] – hIG (mutant) + Protgf-b1 RGD peptide<br />
**[[6uja]] – hIG + Protgf-b1 RGD – Cryo EM<br />
**[[6uja]] – hIG + Protgf-b1 RGD – Cryo EM<br />
 +
**[[7y1t]] – hIG + TGF-b1 – Cryo EM<br />
*IG α-X
*IG α-X
**[[2luv]] – hIG cytoplasmic domain – NMR<BR />
**[[2luv]] – hIG cytoplasmic domain – NMR<BR />
 +
**[[1n3y]] – hIG domain I (mutant)<br />
-
*IG α-X β-2 (CD18)
+
*IG α-X + IG β-2 (CD18)
**[[3k6s]], [[3k71]], [[3k72]], [[5es4]] – hIG + Mg<br />
**[[3k6s]], [[3k71]], [[3k72]], [[5es4]] – hIG + Mg<br />
Line 178: Line 184:
**[[2l1c]] – hIG cytoplasmic tail + SHC<br />
**[[2l1c]] – hIG cytoplasmic tail + SHC<br />
**[[2mtp]] – hIG cytoplasmic tail (mutant) + hIG α-2 β peptide+ filamin rod domain<br />
**[[2mtp]] – hIG cytoplasmic tail (mutant) + hIG α-2 β peptide+ filamin rod domain<br />
 +
**[[6bxb]], [[6bxf]] – hIG/hIG α-L <br />
*IG β-4 (CD104; Gp150)
*IG β-4 (CD104; Gp150)

Current revision

3D structures of integrin

Updated on 31-May-2023

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

Retrieved from "http://52.214.119.220/wiki/index.php/Integrin_3D_structures"
Personal tools