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5c6l

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==Crystal Structure of Gadolinium derivative of HEWL solved using intense Free-Electron Laser radiation==
==Crystal Structure of Gadolinium derivative of HEWL solved using intense Free-Electron Laser radiation==
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<StructureSection load='5c6l' size='340' side='right' caption='[[5c6l]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='5c6l' size='340' side='right'caption='[[5c6l]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5c6l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C6L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C6L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5c6l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C6L FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DO3:10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE+1,4,7-TRIACETIC+ACID'>DO3</scene>, <scene name='pdbligand=GD:GADOLINIUM+ATOM'>GD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DO3:10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE+1,4,7-TRIACETIC+ACID'>DO3</scene>, <scene name='pdbligand=GD:GADOLINIUM+ATOM'>GD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c6l OCA], [https://pdbe.org/5c6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c6l RCSB], [https://www.ebi.ac.uk/pdbsum/5c6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c6l ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c6l OCA], [http://pdbe.org/5c6l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c6l RCSB], [http://www.ebi.ac.uk/pdbsum/5c6l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c6l ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Barends, T R.M]]
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[[Category: Barends TRM]]
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[[Category: Barty, A]]
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[[Category: Barty A]]
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[[Category: Botha, S]]
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[[Category: Botha S]]
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[[Category: Boutet, S]]
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[[Category: Boutet S]]
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[[Category: Caleman, C]]
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[[Category: Caleman C]]
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[[Category: Chapman, H N]]
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[[Category: Chapman HN]]
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[[Category: Doak, R B]]
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[[Category: Doak RB]]
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[[Category: Galli, L]]
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[[Category: Galli L]]
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[[Category: Nanao, M H]]
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[[Category: Nanao MH]]
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[[Category: Nass, K]]
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[[Category: Nass K]]
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[[Category: Santra, R]]
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[[Category: Santra R]]
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[[Category: Schlichting, I]]
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[[Category: Schlichting I]]
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[[Category: Shoeman, R L]]
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[[Category: Shoeman RL]]
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[[Category: Son, S K]]
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[[Category: Son S-K]]
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[[Category: Timneanu, N]]
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[[Category: Timneanu N]]
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[[Category: White, T A]]
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[[Category: White TA]]
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[[Category: Gadoteridol]]
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[[Category: Hydrolase]]
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[[Category: Xfel]]
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Current revision

Crystal Structure of Gadolinium derivative of HEWL solved using intense Free-Electron Laser radiation

PDB ID 5c6l

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