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7g04
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human FABP5 in complex with 7-(4-chlorophenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid== | |
| - | + | <StructureSection load='7g04' size='340' side='right'caption='[[7g04]], [[Resolution|resolution]] 1.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7g04]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G04 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WXZ:(1R)-7-(4-chlorophenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxylic+acid'>WXZ</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g04 OCA], [https://pdbe.org/7g04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g04 RCSB], [https://www.ebi.ac.uk/pdbsum/7g04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g04 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Benz | + | == Function == |
| - | [[Category: Canesso | + | [https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. |
| - | [[Category: Obst | + | __TOC__ |
| - | [[Category: Rudolph | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Benz J]] | ||
| + | [[Category: Canesso R]] | ||
| + | [[Category: Ehler A]] | ||
| + | [[Category: Obst U]] | ||
| + | [[Category: Rudolph MG]] | ||
Revision as of 08:07, 14 June 2023
Crystal Structure of human FABP5 in complex with 7-(4-chlorophenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid
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Categories: Homo sapiens | Large Structures | Benz J | Canesso R | Ehler A | Obst U | Rudolph MG
