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2l86
From Proteopedia
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==Solution NMR structure of human amylin in SDS micelles at pH 7.3== | ==Solution NMR structure of human amylin in SDS micelles at pH 7.3== | ||
| - | <StructureSection load='2l86' size='340' side='right' caption='[[2l86 | + | <StructureSection load='2l86' size='340' side='right'caption='[[2l86]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2l86]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L86 OCA]. <br> | + | <table><tr><td colspan='2'>[[2l86]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L86 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l86 OCA], [https://pdbe.org/2l86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l86 RCSB], [https://www.ebi.ac.uk/pdbsum/2l86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l86 ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment.,Nanga RP, Brender JR, Vivekanandan S, Ramamoorthy A Biochim Biophys Acta. 2011 Jun 23. PMID:21723249<ref>PMID:21723249</ref> | Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment.,Nanga RP, Brender JR, Vivekanandan S, Ramamoorthy A Biochim Biophys Acta. 2011 Jun 23. PMID:21723249<ref>PMID:21723249</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | <div class="pdbe-citations 2l86" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Brender JR]] |
| - | [[Category: | + | [[Category: Nanga R]] |
| - | [[Category: | + | [[Category: Ramamoorthy A]] |
| - | [[Category: | + | [[Category: Vivekanandan S]] |
Current revision
Solution NMR structure of human amylin in SDS micelles at pH 7.3
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