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2lyw

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==Intermolecular interactions between neurotensin and the third extracellular loop of human neurotensin 1 receptor==
==Intermolecular interactions between neurotensin and the third extracellular loop of human neurotensin 1 receptor==
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<StructureSection load='2lyw' size='340' side='right' caption='[[2lyw]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2lyw' size='340' side='right'caption='[[2lyw]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lyw]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LYW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LYW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2lyw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LYW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LYW FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lyw OCA], [http://pdbe.org/2lyw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lyw RCSB], [http://www.ebi.ac.uk/pdbsum/2lyw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lyw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lyw OCA], [https://pdbe.org/2lyw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lyw RCSB], [https://www.ebi.ac.uk/pdbsum/2lyw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lyw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NTR1_HUMAN NTR1_HUMAN]] Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. [[http://www.uniprot.org/uniprot/NEUT_HUMAN NEUT_HUMAN]] Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
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[https://www.uniprot.org/uniprot/NTR1_HUMAN NTR1_HUMAN] Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Costa, G Da]]
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[[Category: Homo sapiens]]
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[[Category: Monti, J]]
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[[Category: Large Structures]]
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[[Category: Interaction ligand/receptor]]
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[[Category: Da Costa G]]
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[[Category: Nts1]]
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[[Category: Monti J]]
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[[Category: Signaling protein-neuropeptide complex]]
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Intermolecular interactions between neurotensin and the third extracellular loop of human neurotensin 1 receptor

PDB ID 2lyw

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