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2npb

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==NMR solution structure of mouse SelW==
==NMR solution structure of mouse SelW==
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<StructureSection load='2npb' size='340' side='right' caption='[[2npb]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2npb' size='340' side='right'caption='[[2npb]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2npb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NPB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2npb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NPB FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Sepw1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2npb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2npb OCA], [https://pdbe.org/2npb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2npb RCSB], [https://www.ebi.ac.uk/pdbsum/2npb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2npb ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2npb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2npb OCA], [http://pdbe.org/2npb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2npb RCSB], [http://www.ebi.ac.uk/pdbsum/2npb PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SELW_MOUSE SELW_MOUSE]] Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency.<ref>PMID:12062442</ref> <ref>PMID:17503775</ref> <ref>PMID:16876868</ref>
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[https://www.uniprot.org/uniprot/SELW_MOUSE SELW_MOUSE] Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency.<ref>PMID:12062442</ref> <ref>PMID:17503775</ref> <ref>PMID:16876868</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/np/2npb_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/np/2npb_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2npb ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Aachmann, F L]]
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[[Category: Mus musculus]]
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[[Category: Dikiy, A]]
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[[Category: Aachmann FL]]
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[[Category: Fomenko, D E]]
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[[Category: Dikiy A]]
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[[Category: Gladyshev, V N]]
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[[Category: Fomenko DE]]
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[[Category: Soragni, A]]
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[[Category: Gladyshev VN]]
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[[Category: Oxidoreductase]]
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[[Category: Soragni A]]
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[[Category: Selenoprotein]]
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[[Category: Thioredoxin-like fold]]
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Current revision

NMR solution structure of mouse SelW

PDB ID 2npb

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