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2rnb

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==Solution structure of human Cu(I)Cox17==
==Solution structure of human Cu(I)Cox17==
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<StructureSection load='2rnb' size='340' side='right' caption='[[2rnb]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2rnb' size='340' side='right'caption='[[2rnb]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2rnb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RNB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RNB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2rnb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RNB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RNB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2rn9|2rn9]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rnb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rnb OCA], [https://pdbe.org/2rnb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rnb RCSB], [https://www.ebi.ac.uk/pdbsum/2rnb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rnb ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">COX17 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rnb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rnb OCA], [http://pdbe.org/2rnb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rnb RCSB], [http://www.ebi.ac.uk/pdbsum/2rnb PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/COX17_HUMAN COX17_HUMAN]] Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity).
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[https://www.uniprot.org/uniprot/COX17_HUMAN COX17_HUMAN] Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rn/2rnb_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rn/2rnb_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Banci, L]]
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[[Category: Large Structures]]
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[[Category: Bertini, I]]
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[[Category: Banci L]]
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[[Category: Ciofi-Baffoni, S]]
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[[Category: Bertini I]]
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[[Category: Janicka, A]]
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[[Category: Ciofi-Baffoni S]]
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[[Category: Kozlowski, H]]
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[[Category: Janicka A]]
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[[Category: Martinelli, M]]
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[[Category: Kozlowski H]]
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[[Category: Palumaa, P]]
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[[Category: Martinelli M]]
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[[Category: Alpha-hairpin fold]]
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[[Category: Palumaa P]]
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[[Category: Chaperone]]
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[[Category: Coiled coil-helix-coiled coil-helix domain]]
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[[Category: Copper binding protein]]
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[[Category: Metal transport]]
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[[Category: Metal-binding]]
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[[Category: Mitochondrion]]
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Current revision

Solution structure of human Cu(I)Cox17

PDB ID 2rnb

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