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2rtu

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Current revision (10:04, 14 June 2023) (edit) (undo)
 
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==Solution structure of oxidized human HMGB1 A box==
==Solution structure of oxidized human HMGB1 A box==
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<StructureSection load='2rtu' size='340' side='right'caption='[[2rtu]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2rtu' size='340' side='right'caption='[[2rtu]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2rtu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RTU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RTU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2rtu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RTU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RTU FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMGB1, HMG1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rtu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rtu OCA], [https://pdbe.org/2rtu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rtu RCSB], [https://www.ebi.ac.uk/pdbsum/2rtu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rtu ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rtu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rtu OCA], [https://pdbe.org/2rtu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rtu RCSB], [https://www.ebi.ac.uk/pdbsum/2rtu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rtu ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/HMGB1_HUMAN HMGB1_HUMAN]] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
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[https://www.uniprot.org/uniprot/HMGB1_HUMAN HMGB1_HUMAN] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Jing, W]]
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[[Category: Jing W]]
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[[Category: Tate, S]]
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[[Category: Tate S]]
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[[Category: Tochio, N]]
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[[Category: Tochio N]]
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[[Category: Disulfide bond]]
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[[Category: Dna binding protein]]
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[[Category: High mobility group box 1]]
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Current revision

Solution structure of oxidized human HMGB1 A box

PDB ID 2rtu

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