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2w9w
From Proteopedia
(Difference between revisions)
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==Solution structure of jerdostatin mutant R24K from Trimeresurus jerdonii with end C-terminal residues N45G46 deleted== | ==Solution structure of jerdostatin mutant R24K from Trimeresurus jerdonii with end C-terminal residues N45G46 deleted== | ||
| - | <StructureSection load='2w9w' size='340' side='right'caption='[[2w9w | + | <StructureSection load='2w9w' size='340' side='right'caption='[[2w9w]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2w9w]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W9W FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[2w9w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Protobothrops_jerdonii Protobothrops jerdonii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W9W FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9w OCA], [https://pdbe.org/2w9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9w RCSB], [https://www.ebi.ac.uk/pdbsum/2w9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9w ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9w OCA], [https://pdbe.org/2w9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9w RCSB], [https://www.ebi.ac.uk/pdbsum/2w9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9w ProSAT]</span></td></tr> | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DIS_PROJR DIS_PROJR] Recombinant protein inhibits the adhesion of alpha-1/beta-1-K562 (ITGA1/ITGB1) cells to collagen IV with an IC(50) of 80 nM.<ref>PMID:16215260</ref> <ref>PMID:21656569</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Calvete | + | [[Category: Protobothrops jerdonii]] |
| - | [[Category: Carbajo | + | [[Category: Calvete JJ]] |
| - | [[Category: Mosulen | + | [[Category: Carbajo RJ]] |
| - | [[Category: Pineda-Lucena | + | [[Category: Mosulen S]] |
| - | [[Category: Sanz | + | [[Category: Pineda-Lucena A]] |
| - | + | [[Category: Sanz L]] | |
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Current revision
Solution structure of jerdostatin mutant R24K from Trimeresurus jerdonii with end C-terminal residues N45G46 deleted
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