This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5fzx
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
==High resolution solution NMR structure of the spider venom peptide U5- scytotoxin-Sth1a== | ==High resolution solution NMR structure of the spider venom peptide U5- scytotoxin-Sth1a== | ||
| - | <StructureSection load='5fzx' size='340' side='right' caption='[[5fzx | + | <StructureSection load='5fzx' size='340' side='right'caption='[[5fzx]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5fzx]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FZX OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5fzx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Scytodes_thoracica Scytodes thoracica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FZX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FZX FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fzx OCA], [https://pdbe.org/5fzx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fzx RCSB], [https://www.ebi.ac.uk/pdbsum/5fzx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fzx ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/U51A_SCYTH U51A_SCYTH] Probable insect neurotoxin with ion channel impairing activity (Probable). Does not show activity on 45 human receptors from 9 families (5-hydroxytryptamine, adrenergic, dopamine, muscarinic, histamine, neurotransmitter, opioid, sigma, and gaba(A) receptors) (PubMed:27227898). In vivo, does not cause paralytic or lethal activity when injected into sheep blowflies or crickets (PubMed:27227898). It is noteworthy that both sheep blowflies and crickets are evolutionarily distant from prey species (PubMed:27227898).<ref>PMID:27227898</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 21: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Scytodes thoracica]] |
| - | [[Category: | + | [[Category: Loening NM]] |
| - | + | ||
Current revision
High resolution solution NMR structure of the spider venom peptide U5- scytotoxin-Sth1a
| |||||||||||
