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5o2p

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==p130Cas SH3 domain PTP-PEST peptide chimera==
==p130Cas SH3 domain PTP-PEST peptide chimera==
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<StructureSection load='5o2p' size='340' side='right' caption='[[5o2p]], [[NMR_Ensembles_of_Models | 40 NMR models]]' scene=''>
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<StructureSection load='5o2p' size='340' side='right'caption='[[5o2p]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5o2p]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O2P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O2P FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5o2p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O2P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O2P FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o2p OCA], [https://pdbe.org/5o2p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o2p RCSB], [https://www.ebi.ac.uk/pdbsum/5o2p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o2p ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o2p OCA], [http://pdbe.org/5o2p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o2p RCSB], [http://www.ebi.ac.uk/pdbsum/5o2p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o2p ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BCAR1_HUMAN BCAR1_HUMAN] Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.<ref>PMID:12832404</ref> <ref>PMID:17038317</ref> [https://www.uniprot.org/uniprot/PTN12_HUMAN PTN12_HUMAN] Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.<ref>PMID:17329398</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5o2p" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5o2p" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Homo sapiens]]
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[[Category: Hexnerova, R]]
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[[Category: Large Structures]]
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[[Category: Veverka, V]]
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[[Category: Hexnerova R]]
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[[Category: P130ca]]
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[[Category: Veverka V]]
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[[Category: Sh3 domain]]
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[[Category: Structure from cyana 3 97]]
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Current revision

p130Cas SH3 domain PTP-PEST peptide chimera

PDB ID 5o2p

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