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5o2v

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==NMR structure of TIA-1 RRM1 domain==
==NMR structure of TIA-1 RRM1 domain==
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<StructureSection load='5o2v' size='340' side='right' caption='[[5o2v]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='5o2v' size='340' side='right'caption='[[5o2v]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5o2v]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O2V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O2V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5o2v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O2V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O2V FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o2v OCA], [http://pdbe.org/5o2v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o2v RCSB], [http://www.ebi.ac.uk/pdbsum/5o2v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o2v ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o2v OCA], [https://pdbe.org/5o2v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o2v RCSB], [https://www.ebi.ac.uk/pdbsum/5o2v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o2v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
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[https://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Jagtap, P K.A]]
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[[Category: Homo sapiens]]
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[[Category: Rna binding protein]]
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[[Category: Large Structures]]
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[[Category: Rrm]]
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[[Category: Jagtap PKA]]
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[[Category: Tia-1]]
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Current revision

NMR structure of TIA-1 RRM1 domain

PDB ID 5o2v

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