This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6xor
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 3: | Line 3: | ||
<StructureSection load='6xor' size='340' side='right'caption='[[6xor]]' scene=''> | <StructureSection load='6xor' size='340' side='right'caption='[[6xor]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full | + | <table><tr><td colspan='2'>[[6xor]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XOR FirstGlance]. <br> |
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xor OCA], [https://pdbe.org/6xor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xor RCSB], [https://www.ebi.ac.uk/pdbsum/6xor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xor ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xor OCA], [https://pdbe.org/6xor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xor RCSB], [https://www.ebi.ac.uk/pdbsum/6xor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xor ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SWA_DROME SWA_DROME] Has a role in localizing bicoid mRNA at the anterior margin of the oocyte during oogenesis, and a poorly characterized role in nuclear divisions in early embryogenesis.<ref>PMID:1806330</ref> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Swallow, a 62 kDa multidomain protein, is required for the proper localization of several mRNAs involved in the development of Drosophila oocytes. The dimerization of Swallow depends on a 71-residue self-association domain in the center of the protein sequence, and is significantly stabilized by a binding interaction with dynein light chain (LC8). Here, we detail the use of solution-state nuclear magnetic resonance spectroscopy to characterize the structure of this self-association domain, thereby establishing that this domain forms a parallel coiled-coil and providing insight into how the stability of the dimerization interaction is regulated. | ||
| + | |||
| + | Structural characterization of the self-association domain of swallow.,Loening NM, Barbar E Protein Sci. 2021 Feb 27. doi: 10.1002/pro.4055. PMID:33641207<ref>PMID:33641207</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6xor" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Drosophila melanogaster]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Barbar E]] | [[Category: Barbar E]] | ||
[[Category: Loening NM]] | [[Category: Loening NM]] | ||
Current revision
Structure of the Self-Association Domain of Swallow
| |||||||||||
