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5cfs

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==Crystal Structure of ANT(2")-Ia in complex with AMPCPP and tobramycin==
==Crystal Structure of ANT(2")-Ia in complex with AMPCPP and tobramycin==
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<StructureSection load='5cfs' size='340' side='right' caption='[[5cfs]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='5cfs' size='340' side='right'caption='[[5cfs]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5cfs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CFS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CFS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5cfs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CFS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CFS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene>, <scene name='pdbligand=TOY:TOBRAMYCIN'>TOY</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene>, <scene name='pdbligand=TOY:TOBRAMYCIN'>TOY</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xje|4xje]], [[5cft|5cft]], [[5cfu|5cfu]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cfs OCA], [https://pdbe.org/5cfs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cfs RCSB], [https://www.ebi.ac.uk/pdbsum/5cfs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cfs ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cfs OCA], [http://pdbe.org/5cfs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cfs RCSB], [http://www.ebi.ac.uk/pdbsum/5cfs PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q6X3H6_PSEAI Q6X3H6_PSEAI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bassenden, A V]]
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[[Category: Large Structures]]
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[[Category: Berghuis, A M]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Rodionov, D]]
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[[Category: Bassenden AV]]
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[[Category: Ampcpp]]
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[[Category: Berghuis AM]]
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[[Category: Antibiotic resistance]]
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[[Category: Rodionov D]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Rossmann fold]]
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[[Category: Tobramycin]]
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[[Category: Transferase-antibiotic complex]]
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Current revision

Crystal Structure of ANT(2")-Ia in complex with AMPCPP and tobramycin

PDB ID 5cfs

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