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5ci8

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==Crystal structure of human Tob in complex with inhibitor fragment 1==
==Crystal structure of human Tob in complex with inhibitor fragment 1==
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<StructureSection load='5ci8' size='340' side='right' caption='[[5ci8]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
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<StructureSection load='5ci8' size='340' side='right'caption='[[5ci8]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ci8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CI8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ci8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CI8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=53Y:PYRROLO[1,2-A]QUINOXALIN-4(5H)-ONE'>53Y</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=53Y:PYRROLO[1,2-A]QUINOXALIN-4(5H)-ONE'>53Y</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ci9|5ci9]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ci8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ci8 OCA], [https://pdbe.org/5ci8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ci8 RCSB], [https://www.ebi.ac.uk/pdbsum/5ci8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ci8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ci8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ci8 OCA], [http://pdbe.org/5ci8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ci8 RCSB], [http://www.ebi.ac.uk/pdbsum/5ci8 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TOB1_HUMAN TOB1_HUMAN]] Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors.
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[https://www.uniprot.org/uniprot/TOB1_HUMAN TOB1_HUMAN] Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bai, Y]]
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[[Category: Homo sapiens]]
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[[Category: Bartlam, M]]
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[[Category: Large Structures]]
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[[Category: Nagatoishi, S]]
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[[Category: Bai Y]]
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[[Category: Suzuki, T]]
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[[Category: Bartlam M]]
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[[Category: Tashiro, S]]
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[[Category: Nagatoishi S]]
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[[Category: Tsumoto, K]]
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[[Category: Suzuki T]]
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[[Category: Yamamoto, T]]
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[[Category: Tashiro S]]
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[[Category: Complex]]
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[[Category: Tsumoto K]]
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[[Category: Inhibitor]]
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[[Category: Yamamoto T]]
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[[Category: Tob/btg family]]
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[[Category: Transcription-inhibitor complex]]
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Current revision

Crystal structure of human Tob in complex with inhibitor fragment 1

PDB ID 5ci8

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